the Editor's Desk
Thanks to all of you (150+ registrants and approximately 40 guests) who attended the meeting in Cincinnati. We truly enjoyed having you here, and your participation made the meeting very memorable indeed. Some of you traveled a long distance to be with us, and we appreciate your effort. The interim meetings are always fun, and stay with us in many ways. Whenever it rains here, I recall the Vancouver meeting because I use the umbrella that was given to us there! On to Little Rock!
This issue of the newsletter is lengthy, but some have been quite thin. The newsletter is an important aspect of life in the Society. Many readers offer that it is among the few missives that they read “cover to cover”. The newsletter helps to bind us as a group, among other functions. Art Weinberg, in his usual thoughtful way, posed several possibilities for the future of the newsletter at the end of his tenure as editor. These and other possibilities were discussed at the Publications Committee meeting at the interim meeting (see below), and the Committee recommended and Council approved reducing the number of issues to two/year, to follow the spring and fall Society meetings. In truth, most of the newsletter is composed of committee reports, and the reports are only available after each meeting. Reducing the number of issues will result in considerable savings to the Society. Let’s live with this plan a while, and see how it suits us. In all likelihood, two issues will be sufficient to accomplish the goals of the newsletter.
Please read the President and President-Elect Messages that follow, as well as the committee reports. The Long-Range Planning Committee has drafted a strategic plan for the Society (see below), and we should all take this opportunity to offer comments, etc. One of the joys of our meetings is seeing pediatric pathology through the eyes of the young, those who hopefully are the future leaders of our specialty. The Distinctions and Awards Committee report gives some detail about the gifted young people who attended the Cincinnati meeting. David Parham provides an important description of the recently-created Children’s Oncology Group, and the place of pathology within that group. Bill Newton is actively involved in enhancing health care for children with cancer in China, and his contribution is truly inspiring. Mark Luquette, the website editor, reminds us to update our email addresses in the website, in order to ensure receiving group mailings from the Society. And by all means, enjoy the photos of the meeting in Cincinnati at the end of the newsletter.
The interim meeting of the Society for Pediatric Pathology in Cincinnati is just over and I have been reflecting on the important role that Cincinnati has played in the development of our Society. No fewer than seven presidents have had a major link with Cincinnati Children's Hospital, and it was a great pleasure to see four of the five surviving members of that elite group at the Meeting. I recall the meeting in Cincinnati in 1983 as a major milestone in my education. For the first time I was privileged to examine the inner workings of a very well-established Pediatric Pathology Laboratory, during which we were introduced to a variety of technical methods that they used. It was very helpful of Dr. McAdams and his staff to present us with a brochure outlining these methods in great detail, including the pitfalls and how to avoid them. I took these methods back to Winnipeg, and then later to McMaster. In Vancouver, and many years earlier, Jim Dimmick had introduced these methods when he returned from his Fellowship at Cincinnati Children’s. For many years of my life, I have been following the procedures developed in Cincinnati and found them of great value, especially the acetylcholinesterase method. The most recent meeting, held 20 years after the first, was the first "all digital" meeting, and after surviving the cultural shock that entailed, I found that the brightness and clarity--not to mention Dr Galambos' amazing animations during his Lotte Strauss Lecture--was a great advance. The meeting introduced us to the advent of gene therapy in the treatment of metabolic disease, and the excellent Symposium opened up new vistas and challenges for the Society's members in the future.
Like all fall meetings, the meeting in Cincinnati called for a tremendous amount of organization and dedication from all the staff at Cincinnati, not least of all the Information Services. I need to thank them from a personal point of view as I am very nervous about "digital" presentations. I enjoyed the Cincinnati meeting and, felt that we have been extremely fortunate in the development of the Society--that each interim meeting seems to add new strength to our Society and sets the bar ever higher for organizers in the future. A special word of thanks to Margaret Collins is essential. She was the contact person for the Society, a key organizer and she did a great job! Thanks, Margaret! I look forward to the next interim meeting in Arkansas, which will be a first for the Society since, as far as I know, we have never met in the Deep South (I am not including Texas!).
The Spring meeting in 2004 is one to look forward to, since it will be the first time that a Spring meeting of S.P.P. and US-CAP will be held in Vancouver. We will be based in the Hyatt Hotel in downtown Vancouver, a short distance away from the US-CAP meeting (in the convention centre by the waterfront). We, in Vancouver, look forward to this event, and we hope that as many people as possible will come to enjoy our fabulous city as well as take part in the meeting. Those who visited Vancouver in 1982 and 2000 for our Interim meetings will know that we have a lot to offer at any time of the year. The weather may be unpredictable, but the lure of our city and the surrounding areas can overcome any minor irritants like rain (or--heaven forbid--snow). Just remember that when it rains in the winter in Vancouver it is snowing in the hills, so that you can work in a little skiing if you wish. Our climate is usually much milder than anything in Eastern or Central Canada.
One of the functions of the president and, perhaps the most enjoyable one, is selecting the Farber-Landing Lecturer. All my professional life, I have been impressed by the overwhelming role that socioeconomic factors play in the health of children. It was pointed out many decades ago that the major factors improving the health of children were in public health, particularly the provision of a safe water supply and adequate nutrition. In our "modern age" this truth remains self-evident. We are, however, faced with a massive looming crisis in at least one continent. An enormous number of children will die from the epidemic of AIDS sweeping across Africa. In some countries of Africa there is, in effect, the almost total deletion of a generation where either the parents have been lost to HIV-AIDS, or the number of economically productive adults has decreased to such an extent that the economy of the country is in dire peril. While in South Africa at the Rhodes Trust Centenary celebrations in January of this year, I was privileged to hear the Rector and Vice Chancellor of the University of the Western Cape, Dr. Brian O'Connell. He is not a physician, but he is an educator in the truest sense of the word. He has a broad range of interests and is an extremely enlightening and commanding speaker. I believe the Society will appreciate hearing him talk on "The socioeconomic aspect of AIDS in children in Africa".
Many different items were discussed at the council meeting in Cincinnati and the committee reports are presented in this Newsletter. One of the important recommendations of council was to draft a small ad hoc committee to design new guidelines and By-laws for the operation of our expanding Web site. The guidelines and related Bylaws will then be passed on to the By-laws Committee to bring to Council in the spring. It is becoming increasingly clear that the Web site offers tremendous opportunities for the education and outreach activities of our Society, and we need to have By-laws that will allow us to run this resource properly, anticipate problems, and create methods for handling them. We are fortunate within the Society to have large numbers of dedicated workers who volunteer their services, time and efforts for the greater benefit of our Society, and the amount of time and effort spent on our Web site is a fine example. Mark Luquette has saved the Society a great deal of money (which would otherwise have been spent on an outside source) by developing an Abstract Form that is server based, improving Web site designs, and introducing hosts of other useful devices that are a mystery to some of us who are a certain age! Thank you, Mark for a job well done!
For those of you who are in the United States a "Happy Thanksgiving" from those of us in Canada who have already celebrated ours! See you in Vancouver March 2004.
There are a number of issues I plan to address during my 2004-2005 tenure:
- increased political action by the SPP in relation to the health needs of infants and children;
- the format of the Spring Meeting;
- a Code of Ethics for our society;
- how we might best assist pathologists in developing countries ( to continue the work begun by Dr. Jaffe and others).
This communication will introduce the membership to some of these topics.
The Format of the Spring Meeting
I plan to appoint a small ad-hoc committee to review the format of the spring meeting and to generate fresh new ideas by the end of 2004. A variety of members from the US, Canada and abroad have voiced concerns about the unfriendliness and alienation they feel when they attend this meeting. We will review all the educational, social, scientific and logistical aspects of the meeting. Please let us know your thoughts so that the SPP can best meet your needs.
Over the past decade many professional societies have adopted ethics codes to guide their members with what they regard as acceptable behavior. During our brief history a very few of our colleagues have engaged in certain activities that have been considered questionable by some of our members. We have not had any guidelines to provide either counsel or sanction. This code of ethics attempts to address some of the most serious concerns.
The Code of Ethics of about a dozen different health related professional societies have been reviewed. Certain portions could be adopted directly by us, or only slightly modified for our use. We want to focus only on those issues that are directly relevant to the SPP and will not duplicate those that are covered by our own institutions or the fact that we are
Over the coming year you will see drafts of a Code of Ethics for the SPP. Please provide input and voice your concerns. Each statement is open to interpretation. This is not a code of law, but merely a collection of guidelines that helps shape our behavior toward one another and our professional responsibility to the public.
Political Action and Child Advocacy
The Society has not had an effective way to influence health related policy at a local or a national level. In the past there has been considerable reluctance to engage in such activity. However there are many issues related to children’s health in which our society’s voice should be added to the debate. Other issues are more specific to us as pediatric pathologists, and require our collective support and attention. Since we are a small society, we will need to partner with larger organizations that have effective lobbying groups and the financial resources to support such activities. There are certainly issues that we could attack directly. Our Society should join, if not lead, the voices of those dedicated to children’s health.
Examples of issues we could be involved with:
|| Outpatient laboratory ‘carve-outs’ in pediatrics by insurance plans;
|| Failure to approve many pediatric-related CPT codes for payment;
|| Malpractice insurance risk group for pediatric pathologists (we get lumped in with all pathologists for insurance purposes);
|| Re-certification (a good or a bad thing depending on one’s perspective);
|| Lobbying the Immigration/Naturalization service to get pediatric pathologists declared an ‘endangered species’ and to relax visa and entry restrictions for foreign trained graduates;
|| Tort reform;
|| Vaccinations and vaccination policy;
|| Use of fetal autopsy data for national health policy planning.
Undoubtedly, you may well have other worthwhile initiatives. We will look for the right committee structure and the people who feel passion about one or more of these to get involved.
Steve Qualman, Chair
The Publications Committee considered a number of topics at the Fall meeting. These topics and their dispositions are summarized below:
|| A motion was passed and approved by Council to limit Newsletter production to twice a year – once each after the Fall Meeting and Spring Meeting.
|| A motion was passed and approved by Council that the website and Newsletter cannot be used for commercial purposes. This does not include internal Society business, and links to external commercial activities can be provided on the website.
|| A motion was passed and approved by Council to redesign the front page of the website to make it more user friendly, subject to Publications Committee review.
|| A motion was passed and approved by Council to appoint a publications subcommittee (Hal
Pinar, Margaret Collins, Mark Luquette) to draft a set of bylaws governing the website (with the Bylaws Committee) for presentation at the Spring Meeting.
|| A motion was passed and approved by Council to empower Jim Crimmins to work with an experienced contract negotiator to review our current contract with the publishers of “Pediatric and Developmental Pathology” in anticipation of contract negotiations coming in the next year; a report will follow at the Spring Meeting.
|| “Perspectives in Pediatric Pathology” is financially solvent with the production of Volume 24. Faculty are encouraged to buy extra copies for their fellows. This is the 30 year anniversary of “Perspectives” Congratulations! Volume 25 is nearly two-thirds complete (Margaret Collins editor – GI Diseases) and Volume 26 (CNS diseases) will be edited by Hannah Kinney.
|| An ad hoc committee (Chairs of the Practice, Education, Research and Publications Committees) suggested to Council (with their approval) use of the “minimum necessary rule” for use of personal health information (PHI) in SPP activities (talks, posters, workshops, etc.). This means that there will not be use of any PHI unless it is absolutely key to the presentation medically. Use of specific patient identifiers requires patient authorization for which the presenter is liable if not obtained. Details of this will follow in a subsequent communiqué after further discussion with the Education Committee.
|| A motion was made by the Committee and approved by Council to empower the PDP editor to push the publisher for electronic submissions as soon as possible.
|| A link was approved by Council from the SPP to CAP websites for current and new CAP Cancer Protocols.
Jeffrey Goldstein, Chair
We would like to commend the membership for their support of our scientific sessions by submitting 67 abstracts for the fall meeting, more than for any previous fall meeting. Forty-two abstracts were accepted (63%) with overall scores for accepted abstracts ranging from 3.17 to 4.58 (mean 3.8) for platforms, and 2.7 to 3.67 (mean 3.1) for posters. All abstracts with scores of less than 2.8 were rejected; seven with scores greater than 2.5 (minimum acceptance score) were rejected on grounds of space/time. Thanks to Laura Finn and her committee for managing and evaluating the abstracts with special thanks to the ad hoc reviewers, Kevin Bove, Charles Timmons, and Edith Schmidt, and to Carolyn Lane at USCAP for her thorough and timely support of the abstract submission process.
The subcommittee is continuing to monitor the impact of increasing abstract submissions on our acceptance rate, particularly at the spring meeting where we currently accept a lower proportion of submissions than USCAP. Adjustments to the meeting schedules may be made to try to accommodate more presentations.
The e-mail based system of abstract submission used for both the fall meeting and the spring 2004 meeting has worked relatively smoothly. Less than 10% of abstracts were submitted by diskette or mailed hard copies. A server based submission form has a number of potential further advantages over the e-mail system, but until now has been cost prohibitive to purchase from vendors. Mark Luquette developed and demonstrated a Web-server based abstract submission process that will be implemented on a trial basis for the Fall 2004 meeting, but authors will be asked to submit abstracts via e-mail as well for back up until the system has proved its reliability. Provided the server solution works as anticipated, e-mail back up will not be requested for subsequent meetings.
Digital projection of abstracts will be implemented for the 2004 spring meeting. David Witte reported that pre-meeting electronic submission of poster discussion slides for the fall meeting went smoothly, but that because of file size, some platform presentations could not be transmitted as e-mail attachments. On-site uploading of presentations from CD-ROMs will be available. Final logistical arrangements will be communicated to presenters of accepted abstracts once the evaluation process for the spring meeting is complete.
Two new workshops will be offered at the spring 2004 meeting: Drs. Gareth Jevon and James Dimmick will present a workshop titled An Histologic Approach to the Pediatric Liver Biopsy, and Debra Heller’s workshop, Pediatric Gynecologic Pathology with Clinical Correlations will also be offered. Four continuing workshops include: Pediatric Dermatopathology: A Practical Approach to Diagnosis by Vijaya B. Reddy and Aliya N. Husain, Vascular Malformations and Tumors in Children by Harry Kozakewich and Paula E. North, Pediatric Soft Tissue Tumors by Cheryl M. Coffin, and Update on Problems and Controversies in Placental Pathology by Rebecca Baergen and Ona Faye-Petersen. Please see the spring meeting registration materials for further information.
Four new workshop proposals were considered for 2005 and 2006; three were approved. Offerings on the horizon for 2005 include a Pediatric Lung Disease workshop by Claire Langston and Tom Stocker, and a Skeletal Malformations workshop by Enid Gilbert Barness and Theonia Boyd. A Head and Neck Pathology workshop by Neena Mirani and John Hicks will be presented starting in 2006.
Daphne DeMello’s developmental pulmonary pathology symposium at the upcoming spring meeting promises to be an excellent program. She has assembled a notable panel of experts to address issues and recent advances in lung biology. Further information is also in the spring meeting materials.
The spring 2005 symposium is a milestone as it will be the Society’s first symposium jointly organized with one of the USCAP companion societies, the Binford Dammin Infectious Disease Society. David Walker has agreed to serve as the moderator for this pediatric infectious disease symposium, and he is working with the Binford Dammin Society program committee to develop a program of interest to our combined memberships based in part on responses Debra Heller received to an e-mail survey conducted through the SPP listserver. The symposium will move from its usual time slot on Saturday afternoon to Sunday morning to accommodate the joint program.
Many thanks to David Carpentieri and Deb Heller for their coordination of the SPP’s upcoming didactic sessions.
Lisa Teot asks all Workshop and Symposium presenters to route all course handouts through the SPP office so that they can ensure that Objectives and appropriate Disclosure statements are included in the printed versions. Presenters should not print handouts and bring them to the meeting themselves.
Lisa also discussed the ACCME’s preference for outcomes based (rather than satisfaction) evaluations of educational activities. To facilitate this type of evaluation, some program objectives need to be written with outcomes in mind. Lisa will prepare a discussion of this process which will appear in a future newsletter to assist program presenters.
Little Rock 2004 – The meeting will be held October 28-31, 2004 and will feature a symposium: Modern Pediatric Forensic Pathology. David Parham has planned an excellent combination of scientific sessions and social activities that we all look forward to next fall.
Tours, France 2005 -- in conjunction with the Paediatric Pathology Society (PPS). The meeting will include scientific sessions Thursday and Friday, September 1-2, 2005 with a tour of the Loire Valley on Saturday, September 3, 2005. The European Congress of Pathology meeting starts on Sunday September 4, 2005, in Paris. Liliane Boccon-Gibod is coordinating on site logistical arrangements. Tours is accessible by fast train from the Paris airport, and will provide a more intimate and less expensive venue for this meeting than being in Paris itself.
Two proposals were considered for fall 2006. The committee selected the Columbus Children’s Hospital, Columbus, OH, and Steve Qualman as the hosts for the 2006 fall meeting.
Council accepted the Committee’s recommendation for the SPP to sponsor a freestanding perinatal-placental course developed by Ona Marie Faye-Petersen and other members of the Perinatal Section. Ona is to be congratulated for her persistent efforts to develop this course, another first in SPP history. The course outline and proposed faculty are excellent. Mark your calendars for the Omni Parker Hotel in Boston, May 20-22, 2005, and watch for a more detailed program description on www.spponline.org
Lisa Teot brought to the Committee’s attention the impending requirement by the American Board of Pathology for re-certification of pathologists now in training, and of the potential impact on voluntary re-certification of those currently “grandfathered”. The Committee agreed with her sense that the SPP needed to have input into examination content and format for re-certification of pediatric pathologists. In their published materials, the Board appears receptive to involvement of sub-specialty societies in this process. Over the coming months, members of the Education Committee will be working with the Executive Committee to establish contacts with the ABP to begin these discussions.
Gareth Jevon, Chair
The Practice Committee had a productive Fall Meeting in Cincinnati. The committee discussed the potential benefits of digital microscopy to the case study survey. In addition to the usual glass slides, the next survey will include an extra test case for evaluation. The test case will be a case that does not have sufficient tissue for sectioning and distribution to members. Images of the test case, including routine histology and special stains, will be accessed through the SPP website as a trial. The requested feedback will be evaluated.
Mary Davis continues to gather data from individuals for the completion of her membership practice profile survey, an important contribution to the practice of this subspecialty. The initial results have indicated a serious shortage of trainees and younger members in pediatric pathology practice, accentuating the shortfall due to attrition in the near future.
The Practice Committee will also begin to evaluate the practice and contribution of the pediatric autopsy in the expectation that its contribution to quality improvement in children's health care may be highlighted.
Alba Greco, Chair
Fellow duty hour standards
Beginning July 1, 2003, all ACGME accredited programs must comply with duty hour standards. These new standards apply to all accredited specialties and subspecialties. They will be posted on the SPP Web Site. For more information see ACGME Web Site (www.acgme.org).
ACGME Outcome Project
The ACGME requires that accredited programs have the potential to educate fellows and now, in addition to that, programs should document the education has taken place by assessing the outcome. For this purpose, the ACGME designed the competency-based model. Definition of competencies and examples of assessments pertinent to Pediatric Pathology will be posted on the SPP Web Site.
LONG TERM PLANNING COMMITTEE
Cheryl Coffin, chair
Society for Pediatric Pathology
Long Term Planning Committee Meeting
Saturday, October 18, 2003
Present: Cheryl Coffin, Atilano Lacson, Charles Timmons, Halit Pinar, Denis Benjamin, and Derek DeSa
Excused: Trevor MacPherson
|| Minutes of the September 28, 2002, Long Term Planning Committee Meeting were approved.
|| The charge to the Long Term Planning Committee was reviewed (see SPP Bylaws, Article IV, Section 6b).
- Action item: Consider a bylaws change at Fall, 2004 meeting of Long Term Planning Committee.
|| Past Long Term Planning Committee accomplishments (See attached summary).
|| Meeting time. Future Long Term Planning Committee Meetings will be held at the Fall (Interim) meeting of the Society for Pediatric Pathology on Thursday for 1 hour, prior to the scheduled time for the SPP Council meeting.
|| Draft Strategic Plan. See attached draft.
|| The top strategic priorities from the Fall, 2002, Long Term Planning Committee meeting included: manpower and recruitment; scholarship, research, and academic development; practice standards and clinical excellence; value of pediatric pathology as a specialty from the clinical perspective; and outreach.
|| The draft strategic plan prepared in advance of the 2003 Committee meeting was reviewed and revised. The revised draft is attached.
|| The revised draft strategic plan will be circulated to the SPP Council and committee chairs for their review and suggestions. Cheryl Coffin will circulate the revised draft to Long Term Planning Committee members, and Hal Pinar will distribute it to committee chairs, SPP Council members, and Margaret Collins.
|| The draft strategic plan will be published in the Fall, 2003, SPP Newsletter, and further suggestions will be solicited.
|| Final revisions will be completed by January 15, 2004, and will be given to Council for final approval at the March, 2004, Council meeting.
|| The final version of the strategic plan will be placed on the SPP website.
|| Annual review of the strategic plan and recommendations for changes will be done under the auspices of the SPP Council and Long Term Planning Committee in the future.
- Action item: Denis Benjamin, Derek DeSa, Hector Monforte, and Henry Krous will prepare a specific set of recommendations for outreach by the Society for Pediatric Pathology and its members and will present it at a future committee meeting. (See September 28, 2002, minutes).
|| Future Plans: A bylaws change will be proposed at the March 2004, Council meeting: “The Chair of the Liaison Committee shall be appointed by the SPP council for a 3-year term”. This proposal resulted from a discussion during review of the strategic plan and the recognition of the important roles of the Liaison Committee.
|| The next meeting of the Long Term Planning Committee will be held at the Fall 2004, SPP meeting in Little Rock, Arkansas.
Revised Draft of Strategic Plan
DISTINCTION AND AWARDS COMMITTEE
Society for Pediatric Pathology
October 20, 2003
Antonio R. Perez-Atayde, Chair
Awards for scientific presentations at the Cincinnati meeting
This year’s winners of the Resident’s Case Report were Kudakwashe Chikwava, M.D. from the Department of Pathology, University of Pittsburgh whose poster was entitled “Acute Ethanol Intoxication in a Seven Month-Old Infant”;
Kelly Grove Nigro, M.D. from the Department of Pathology, University Hospitals of Cleveland whose poster was entitled “Cytodifferentiation, but not resolution, of embryonal rhabdomyosarcoma”; and
Mana M. Parast, M.D., Ph.D. from the Department of Pathology and Laboratory Medicine, Emory University School of Medicine whose poster was entitled “Renal Carcinoma with Xp11.2 Translocations/TFE3 Gene Fusions in a Three-Year-Old Child”.
On behalf of the Selections Committee congratulations for the great work!
This year we had over 30 applicants with excellent contributions addressing the uniqueness of pediatric pathology. The committee’s decision to select the three best abstracts was a very difficult one and we thank all participants for their excellent contributions. We hope that all the participants consider pursuing a career in pediatric pathology.
The Society for Pediatric Pathology established the Resident's Case Presentation Award to encourage residents to consider careers in pediatric pathology. The three awardees attended the interim meeting in Cincinnati and presented their posters. Each of the awards consist of the following:
Travel, registration, and lodging costs to attend the 2003 interim meeting October 16-18 in Cincinnati, Ohio.
Poster presentations of award-winning case reports.
Lunch with "Legends in Pediatric Pathology" (lunch at interim meeting with two or three well-known pediatric pathologists).
Publication of the resident's case report in special section of
Pediatric and Developmental Pathology
Complimentary subscription to Pediatric and Developmental Pathology
At the meeting in Cincinnati, one individual was recognized for meritorious scientific effort. The
Vawter Pathologist in Training Award was presented to Dr. L. Ernst from Yale University School of Medicine, New Haven, CT for her paper: “PCR FOR 16S rRNA DNA NOT SUPPORTIVE OF BACTERIAL ETIOLOGY FOR CHRONIC VILLITIS”. Coauthors are J.Crouch, MS, H. Rinder, MD, J. Howe, PhD. Yale University School of Medicine, New Haven, CT.
Abstract Vawter Award:
PCR FOR 16S rRNA DNA NOT SUPPORTIVE OF BACTERIAL ETIOLOGY FOR CHRONIC VILLITIS. L. Ernst, MHS, MD, J.Crouch, MS, H. Rinder, MD, J. Howe, PhD. Yale University School of Medicine, New Haven, CT
Subject of study: Chronic villitis is an inflammatory condition in the placenta in which the chorionic villi are infiltrated by lymphocytes, histiocytes and sometimes plasma cells. In a small percentage of cases, an infectious agent can be demonstrated within areas of chronic villitis. However, the majority of lesions are idiopathic. Chronic villitis may represent direct spread of chronic endometrial infection by bacterial organisms that are problematic to culture. In order to test this hypothesis, PCR using primers for universal bacterial 16S rRNA DNA was performed on DNA extracted from
areas of chronic villitis.
Methods: Cases of chronic villitis were selected from the Yale Pathology database. Specific areas of chronic villitis were confirmed by examination of H& E sections and removed from archived paraffin blocks. Tissue spiked with known bacterial counts was also prepared to test sensitivity of the experiment. All tissue was deparaffinized, dehyrated, and digested with proteinase K. DNA extraction was performed by the Gentra Purgene kit. PCR using 300ng of extracted DNA was done using primers p11 and p13 for the 16SrRNA DNA. The 233bp amplified target product was identified on agarose gel following electrophoresis.
Results: Nineteen specimens were studied, all of which showed chronic villitis that was multifocal and not confined to anchoring villi. DNA with satisfactory 260/280 OD ratios was obtained on all specimens. Amplification of a 440bp segment of the beta-globin gene was present in all specimens indicating that a smaller product could be amplified. None of the chronic villitis specimens had a demonstrable product using the PCR primers for 16S rRNA DNA. The assay was sensitive to approximately 1500 bacteria in the specimen.
Conclusions: This study does not support a bacterial etiology for chronic villitis composed of lymhocytes, histiocytes and plasma cells, despite the similarities to the histology of chronic endometritis.
The Neustein "Novel Technology" Award was not given this year.
The Lotte Strauss Prize, which is awarded annually to the author of the best paper published on a subject germane to pediatric pathology in the preceding year by an individual 40 years of age or younger, was awarded to Dr. Csaba Galambos, M.D. during the Spring meeting in Washington DC. He received the prize as first author of the paper:
DEFECTIVE PULMONARY DEVELOPMENT IN THE ABSENCE OF HEPARIN-BINDING VASCULAR ENDOTHELIAL GROWTH FACTOR ISOFORMS, published in the American Journal of Respiratory Cell and Molecular Biology, 2002;27:194-203. During the Fall Meeting in Cincinnati, he gave the
LOTTE STRAUSS LECTURE about this work. Dr. Galambos is currently an Assistant Professor in Pediatric Pathology at the Children's Hospital of Pittsburgh, and was formerly at the Department of Pathology in Saint Louis University Health Sciences Center and Cardinal Glennon Children's Hospital, Saint Louis, Missouri, where he performed the work that culminated in the prized paper. Between these two positions he finished successfully a Pediatric Pathology Fellowship at the Children’s Hospital of Boston.
Eligibility criteria and application guidelines for the 2003 Lotte Strauss Prize are available online on this SPP website. The deadline for the application is Jan. 1, 2004.
CHILDREN’S ONCOLOGY GROUP
The Role of the Pathology Discipline Committee
David M. Parham, MD, Chair
Effective March 2000, four major inter-institutional pediatric cancer treatment groups merged into a single entity, the Children’s Oncology Group. The four merger groups comprised the Children’s Cancer Group (CCG), Pediatric Oncology Group (POG), Wilms’ Tumor Study Group, and Intergroup Rhabdomyosarcoma Study Group. With this merger the groups formally pledged to combine their efforts to accelerate the goals of curing and eventually preventing cancer in children and adolescents. The event marked the beginning of a new era in the fight against childhood cancer and signaled the willingness of previously separate groups to pool their resources for this vision.
The Children’s Oncology Group consists of committees that oversee three types of activities. Disease Committees are comprised of individuals with interest and expertise in specific types of childhood cancer. These include acute lymphoblastic leukemia, acute myeloblastic leukemia, Hodgkin lymphoma, non-Hodgkin lymphoma, neuroblastoma, bone tumors, soft tissue tumors, central nervous system tumors, renal tumors, eye tumors, and rare tumors (primarily liver, germ cell, and miscellaneous epithelial neoplasms). Pathology representatives sit on each of these committees and participate in study design and analysis, as well as serving as pathology reviewers in most.
Discipline Committees are comprised of specialists that participate in the diagnosis, treatment, and data analysis of childhood cancer. Besides the Pathology Discipline Committee, these include Surgery, Nursing, Radiation Oncology, Cytogenetics, Clinical Research Associates, Psychology, Diagnostic Imaging, Laboratory Science, Pharmacy, Statistics, Hematology/Oncology, Neurology, and Stem Cell Transplantation. As a result of discussions held during the transitional period prior to the group merger, an additional Biopathology and Translational Research Committee was created. This group consists of the Pathology Discipline Committee, the Biopathology Center, the Cytogenetics Committee, and the Laboratory Science Committee and exists to promote interchange of ideas and resources to facilitate research in pediatric cancer. Other special scientific groups include the Developmental Therapeutics, Epidemiology, Late Effects, Cancer Control, Nutrition, and Adolescent/Young Adult Committees.
Administrative Committees are comprised of members that oversee group functions and regulations, such as the Membership Committee, Executive Committee, Information Advisory Committee, Data Monitoring Committees, Bioethics Committee, Industry Relations Advisory Committee, Scientific Chairs Committee, Patient Advocacy Committee, Institutional Performance Monitoring Committee, Minority Subjects Advisory Committee, Young Investigators Committee, the Voting Body, and the Scientific Council. Representatives from the Pathology Discipline Committee sit on many of these administrative committees; for example the Chair of the Pathology Discipline Committee serves on the Executive Committee and Scientific Chairs Committee, and other members serve on the Membership, Information Advisory, Data Monitoring, and Young Investigators Committees.
For funding and monetary transfer, the Children’s Oncology Group uses the National Childhood Cancer Foundation (NCCF) as a grantee organization. Initially, the University of Southern California served this role for the CCG, and Northwestern University played a similar role for the POG. However, the indirect costs paid to these institutions was costly, so the CCG founded the NCCF to lower costs taken from federal funds to support their initial sponsor. The NCCF continues to be the grantee organization for COG. As such NCCF conducts charitable fundraising and administers research funding, the latter primarily from the National Cancer Institute. Any costs not funded from research budgets must be paid by the charitable branch of the NCCF. The NCCF is run by a Board of Trustees, and the Chairmen of the COG and the Scientific Advisory Board serve as ex officio members. The Scientific Advisory Board serves the Board of Trustees in an advisory capacity relating to scientific and medical affairs, but its members do not have a similar responsibility for the COG.
The Chair of the Pathology Discipline Committee serves a five year term, after election by a vote of the entire Committee. As well as serving on the Executive and Scientific Chairs Committees, the Pathology Discipline Chair must coordinate the COG pathology meetings, approve COG appointed pathology reviewers, approve COG pathology budget expenditures (including travel), prepare the Pathology grant proposal and budget and work with the site visit team, and serve as the pathology liaison to the COG office, Biopathology Center, and BTRC. To assist in these duties, the Chair may appoint a small Steering Committee that includes representatives to certain administrative committees.
Besides the Chair, Administrative Committee members, Disease Committee members, and Steering Committee, the Pathology Discipline Committee comprises all institutional pathologists who are COG members. Associate membership requirements are defined by the Pathology Discipline and Membership Committees and currently include 1)Board certification or equivalent, and 2) interest in pediatric cancer pathology. Membership applications must also be approved by the institutional Principal Investigator (PI), generally a member of Hematology/Oncology. There are no limits on the number of pathologists from an individual institution who may apply, and membership allows one to access the Webpage (http://members.childrensoncologygroup.org) in order to learn protocol requirements, read committee minutes, register for meetings, and access the administrative manual. Full membership requires that in addition to the above requirements, the individual must attend at least two meetings every three years. Full membership is required for voting in COG-wide elections (not discipline committee elections) and may be needed for participation in some Disease and Administrative committees.
A major function of institutional pathologists is to serve as Responsible Investigators (RI) in Pathology. Each institutional PI must select one RI in Pathology, whose role is to assume responsibility for institutional compliance in pathology. This person will receive correspondence regarding group studies and activities relative to pathology. Associate membership is required.
Other pathology-related requirements for institutions include the following: 1)at least one board-certified pathologist must be available and must be committed to handling specimens per COG study requirements, 2)anatomic pathology services must be available on site for the immediate handling of specimens for frozen section diagnosis and storage, 3)laboratory services must be available 24 hours a day for therapeutic apheresis, immediate stains for organisms, transfusion of blood products (including leukocyte-reduced, irradiated products), and routine blood gas, coagulation, hematology, and chemistry examinations on pediatric samples. Although not necessarily on site, the laboratory must have access to CLIA-approved (or equivalent) laboratories offering 1)cell marker studies, 2) bone marrow aspirate and biopsy analysis, 3)histopathology, 4)cytogenetic analysis, 5)immunohistochemistry, 6)comprehensive microbiology and virology, and 7)clinical chemistry monitoring for antibiotic and methotrexate levels. Subspecialists with certification and/or special training in pediatric pathology, hematopathology, and neurology must be readily accessible. For comprehensive hematology/oncology programs, multiple disciplines including pathology must participate in regular tumor board discussions. Finally, the hematology/oncology program must be affiliated with or part of a hospital and laboratory that are approved for the care of children by JCAHO or its equivalent.
The Pathology Discipline of the COG has three major functions: review of pathologic materials, banking and use of tumor tissues for research, and education of institutional pathologists. Reviewers are primarily selected by Disease Committee Chairs and are approved by the Pathology Discipline Chair. Reviewers must be committed to timely, accurate review of materials submitted by institutional chairmen. The table below lists the roles and expectations of Pathology reviewers.
Tumor banking is primarily carried out under the auspices of the Biopathology Center in Columbus, Ohio, currently directed by Dr. Steve Qualman. The Biopathology Center is charged with providing diagnostic confirmation of disease in patients on solid tumor and AML studies, a uniform pathologic approach to diagnosis, a central repository for pathologic materials, and a central tumor procurement facility. The latter provision is carried out by the Cooperative Human Tissue Network (CHTN;http://www.chtn.ims.nci.nih.gov/), which receives NCI support to provide medical researchers with human tissues. Since its inception in 1987, the CHTN has provided over 500,000 specimens to over one thousand investigators. The Director of the Biopathology Center reports to the Pathology Discipline Chairman in matters of pathology review, and to the BTRC Chairman for issues concerning scientific material.
Education in COG Pathology takes several forms and includes a pathology symposium at the COG meeting, a lecture and update at the fall Society for Pediatric Pathology meeting, and a young investigator program pairs young pathologists with COG mentors, primarily reviewers. The goal is to educate general pathologists and well as pediatric specialists, because many if not most COG member institutions are served by general hospitals. To help meet this goal, educational materials and meeting minutes will be maintained on the Discipline section of the COG member website.
Role of COG Pathology Reviewers in Scientific, Discipline, and Study Committees
Approved by Pathology Discipline Committee, 4/19/01
David M. Parham, MD, Chairman
|| The COG Discipline of Pathology exists for two purposes: advancement of science and care of patients. Care of patients takes precedence over science.
|| The primary purpose of pathology review in COG is to assure the quality of pathology data submitted for statistical analysis.
|| Pathology reviewers should be available for consultation by institutional pathologists as needed to determine protocol eligibility.
|| In order to prevent conflicts in patient management, pathology review should be conducted in a timely fashion as defined by protocol.
|| Pathology reviewers should be compensated for their time and expertise in an appropriate fashion, both academically and financially.
|| Pathology reviewers should take an active role in protocol design and modification, based on their training, experience, and knowledge of new information.
|| Pathology reviews should actively participate in the design and conduct of biologic studies in their scientific committee.
|| Pathology reviewers should maintain an active knowledge of new pathology literature concerning the neoplasms treated by their scientific committee.
|| Pathology reviewers should actively contribute to the pathology literature as authors of original and review articles.
|| Pathology reviewers should encourage participation by younger and secondary reviewers and should actively groom successors.
|| Secondary review should be encouraged, but one pathologist should assume the role of “tie-breaker” in each discipline. Outside consultation should be utilized as needed in the judgment of the reviewer.
|| Pathology reviewers should attend COG meetings on an annual basis at minimum and apply for full membership.
International Consortium for CURE of Childhood Cancer in China:
Background and Current Status
William A. Newton, M.D.
While in Japan in 1991, Dr. Bill Newton, Past Director of The Department of Laboratory Medicine and the Division of Hematology/ Oncology at Children’s, was asked by a Japanese pathologist who had spent six months as a pathology resident at Children’s Hospital, “Why don’t you help China?” That was an entirely new thought. The reply was, “What could I do for such a big country, and would they want me to do that?” The pathologist replied, “Let’s go ask”. He had been interested in China for many years, and had been spending most of his time training Chinese pathologists in electron microscopy. In the next two years he worked to arrange a series of Sino-Japanese scientific conferences in a series of some of the larger Chinese cites in eastern and central China. This enabled Dr. Newton to talk to those that were caring for children with cancer in these cities. One of those was Dr. Hu Ya Mei, the leading pediatrician in China, who was in charge of treating children with leukemia at Beijing Children’s Hospital, the largest children’s hospital in China. When she heard of the success in curing children with cancer in the US she replied, “We need help to do the same. Will you help us?” Only about five percent of China’s cases are cured, in contrast to an over all cure rate in the US of 80%.
With Dr. Hu’s help, and with funding from a variety of sources, including the International Office of the US National Cancer Institute, the World Health Organization, private funds from the Japanese pathologist and others, a series of conferences on childhood cancer were held in various Chinese cities. These were attended by many of those who treated Chinese children with cancer, including most of the specialist types involved. The lectures were given by world leaders from the US, Europe, and Asia representing all aspects of diagnosis and treatment. Following a week-long conference in Guangzhou in 1999, Dr. Newton and Dr. Gerald Haase, agreed that lecturing to Chinese in English with interpreters was not an effective way to help China. The decision was made to establish a new way to do this. By adding representatives of business and government to a team of pediatric cancer specialists, the seemingly overwhelming task could be more successful. Surprisingly, the concept and the need was uniformly accepted by all those asked to join in the effort. This led to incorporation, and IRS approval as a 501 C (3) private nonprofit organization in early 2000, with headquarters at Children’s Hospital of Columbus. The organization’s name is The International Consortium for CURE of Childhood Cancer in China, or CURE for short. It was given the title of “International” since those who agreed to serve were from all over the world, mostly the US, but also Europe, Asia, and Australia.
The next step was to find a way for CURE to have a counterpart organization in China, so that its efforts would be aimed at assisting and supporting, and not directing. This came about because of the addition to CURE of a Chinese trained physician at Ohio State University who was looking for ways to help his mother country. CURE’s goal to assist China increase the cure rates of children diagnosed with cancer was just what he wanted. Through his Chinese relationships he was able to identify and bring about a partnership between CURE and the leading private agency in China whose goals are to improve Chinese child and maternal health and culture, The Soong Ching Ling Foundation (The China Welfare Institute) (SCLF/CWI). This organization was started and led for many years by the wife of China’s highly respected pioneer revolutionary, Dr. Sun Yat Sen. The SCLF/CWI has formed a separate foundation within its structure, and will administer all of CURE’s activities in China. SCLF/CWI agreed to raise funds for children with cancer in China, and to date has raised over $125,000. With funding from NIH, and McDonald Children’s Charities, representatives of CURE and SCLF/CWI met in March of 2002 to teach/learn about cancers in children, and to receive proposals from Chinese physicians who had ideas to study which could develop local and national models for future expansion and improvement. Nine proposals were presented at that meeting. Later, representatives of CURE and China selected three of these projects for CURE’s initial assistance and support.
CURE’s Structure and Relationship to other Organizations
CURE is composed of representatives of pediatric cancer medicine, US businesses, and government. All have agreed to serve as volunteers. Most are world famous, and do not expect that their efforts will lead to personal or institutional aggrandizement. Dr. Newton serves as President, and Dr. Haase as Vice President. CURE has succeeded in developing acceptance and trust in Chinese leaders, and has made efforts to cooperate with every other organization that has the same goal for China. Some of these include The Children’s Oncology Group, The International Society for Pediatric Oncology, the National Cancer Institute, The US State Department, International Offices of The Department of Human Health and Services, The International Network for Cancer Treatment and Research, The St. Jude International Outreach Program, and Project Hope.
Project 1. CURE will assist and support infrastructure costs and training needs for the already existing inter-institutional cooperative childhood cancer group that cannot function well because of lack of support. This group consists of about 15 university centers treating cancers of children willing to adopt the approach that has been so successful in increasing cure rates of children with cancer in the US and other industrial countries. Their efforts were limited to the study of only one form of lymphoma, which they completed and published. CURE predicts that these centers will be the “hub” of regional care programs, as “Centers of Excellence”. They would also be the leaders in research of childhood cancer.
Project 2. The only center in China that has developed the level of care to approximate the level in the US will study how a regional hospital can be trained to be the primary site of diagnosis of children’s cancer, and enabled to treat those that can be successfully treated with limited resources.
Project 3. A large metropolitan area in SE China has succeeded in developing a local cooperative group of seven hospitals that treat children with acute leukemia on the same protocols, with assistance from experts from Hong Kong. These institutions are to study how several hospitals can develop a way to function as a “Center of Excellence” for their region. They will identify the kinds of experts and facilities that will be required, and by planning can have all of the services required.
As CURE projects get activated, CURE would welcome the interest and involvement of those who would be willing to share their experiences with their Chinese counterparts in this challenging project.
The editor had the distinct pleasure of spending a week funded by the McAdams Short-Term Study Stipend in Pittsburgh with Ron Jaffe and his staff, particularly Maria Parizhskaya, to study small bowel transplant biopsies. The McAdams Stipend is really a great way for pediatric pathologists to broaden their horizons. I wish all future McAdams awardees (see below for information) to gain as much knowledge, given with as much kindness, as I did in Pittsburgh.
McAdams Stipend hosts (from left to right): Lisa
Teot, Ron Jaffe, Sarangarajan Ranganathan, Raj Hari, Kudakwashe Chikwava (KC),
Mike Caplan, Maria Parizhskaya. KC presented one of the resident case
presentations at the interim meeting in Cincinnati.
Meeting, March 6-7, 2004, Vancouver, BC, Canada
Paediatric Pathology Society Golden Jubilee Congress
Cape Town, South Africa, April 22-24, 2004
- Detailed information is available from: Ms Deborah McTeer:
- Preliminary information is also available from the University of Cape Town website: www.uct.ac.za/depts/pgc where one needs to seek events during 2004 and go to paediatric pathology. The congress will be preceded by an update course in Paediatric and Paerinatal Pathology for a limited number of early registrants. This will be at a Spa in the mountains of the Western Cape about 50 kilometers from Cape Town. Roc Kaschula is the local organizer:
11th Latinamerican Congress of Pediatric Pathology
35th Colombian Congress of Pathology
CARTAGENA COLOMBIA. September 23-25, 2004
PRELIMINARY SCIENTIFIC PROGRAM:
Pediatric Oncology: Vascular lesions/tumors, Hepatic tumors: prognostic factors, Retinoblastoma,
Pediatric tumors in Colombia
Perinatal pathology: Perinatal Necropsy, Iatrogenic lesions
Nephropathology: Nephrotic Syndrome, New Glomerular diseases
Neuropathology: New Brain tumors, Pathology of Epilepsy
Gastrointestinal Pathology: Hirshsprung disease and related conditions
Hematopathology: Non infectious pathology of lymph nodes
Osteoarticular Pathology; Osteochondrodysplasias
Molecular Pathology: Diagnostic aspects of non neoplastic diseases
Fax 571 3165000 ext 15177
Phone number 571 2148961
Cl 101 # 13 23 APT 301 BOGOTA COLOMBIA SOUTH AMERICA
SPP Interim Meeting, October 28-30, 2004, Little Rock, AK, USA
Perinatal Symposium October 31, 2004
Click here for more information
CALL FOR NOMINATIONS
Lotte Strauss Prize
The Lotte Strauss Prize recognizes meritorious work by an individual 40 years of age or younger in a subject germane to pediatric pathology, published or accepted for publication during the 2003. The winner, who will receive a $1000 cash prize and expenses to attend and present at the fall 2004 meeting of the Society, will be announced at the spring 2004 SPP meeting. Nomination requires submission of five copies of the completed paper, a letter from the nominee, sponsor (if the nominee is not an SPP member), and five copies of the nominee's curriculum vitae. If anyone has any questions please contact or call Dr. Perez-Atayde at the number below.
Please send submissions by January 1, 2004 to:
Antonio R. Perez-Atayde MD
Department of Pathology
300 Longwood Avenue
Boston, MA 02115
CALL FOR APPLICATIONS
Young Investigator Research Grant
|| To foster research within the SPP by providing funds to young investigators in the field of pediatric pathology.
|| To fund a pilot project which will lead to long-term research support from other granting agencies.
Use of Funds: The funds are to be used to facilitate basic or applied research by a young investigator in the field of pediatric pathology. Research into any aspect of pediatric disease will be considered, including morphological, biochemical, behavioral, physiological, genetic, and epidemiological studies. Appropriate expenditures include capital equipment, reagents and supplies, research-related travel, salary supplementation, service costs (e.g., electron microscopy, histology), and animal care costs. Indirect costs are not allowed.
Eligibility: Applicants must be
- a MD, PhD, DDS, DVM, or DO AND
- either a resident or fellow, full-time, in an accredited pathology training program or
a faculty/staff person in pediatric pathology for less than 5 years, or working in the laboratory of a faculty/staff person in pediatric pathology AND
- either a member of the SPP or sponsored by a member of the SPP
Amount of Award: An annual award of $10,000 will be made.
Selection Process: Complete applications must be received by the Research Committee no later than February 1, 2004. They will be reviewed by the Committee and the award will be announced at the SPP meeting in March. Consideration will be given to scientific merit and the background and career goals of the applicant. Award funding will begin July 1, 2004.
Application Instructions: Application instructions can be downloaded. Submit 6 copies of the completed form to:
Gail H. Deutsch, M.D., Chair of the Research Committee, Department of Pathology – MLC1010, Cincinnati Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229-3039 Additional inquires can be directed to Dr. Deutsch
A. James McAdams Short-Term Study Stipend
Background: The Society for Pediatric Pathology and Children’s Hospital Medical Center of Cincinnati established the Short-Term Study Stipend to honor A James McAdams, M.D, by promoting opportunities for pediatric pathologists to learn investigative techniques that are not available at their institution.
|| To honor the memory of A. James McAdams, M.D.
|| To facilitate training of pediatric pathologists in investigative techniques available at other institutions.
Use of Funds: The funds may be used to offset travel and living expenses incurred by a pediatric pathologist who visits another institution in order to develop new research skills related to either clinical or laboratory investigations.
Eligibility: Applicants must be
- a MD or DO AND
- either a resident or fellow, full-time, in an accredited pathology training program or
a faculty/staff person in pediatric pathology AND
- either a member of the SPP or sponsored by a member of the SPP
Amount of Award: An annual award of up to $2,000 will be made to support travel and living expenses for up to one month.
Selection Process: Complete applications must be received by the Research Committee no later than February 1, 2004. They will be reviewed by the Committee and the award will be announced at the SPP meeting in March. Consideration will be given to scientific merit, the background and career goals of the applicant, the expertise and/or resources available at the remote institution. Award funding will begin July 1, 2004.
Application: An application can be downloaded directly from this website or can be obtained by mail from the
Society for Pediatric Pathology
C/O United States and Canadian Academy of Pathology (USCAP)
3643 Walton Way Extension
Augusta, GA 30909
Completed applications should be sent to:
Gail H. Deutsch, M.D.
Chair of the Research Committee
Department of Pathology – MLC1010
Cincinnati Children’s Hospital Medical Center
3333 Burnet Avenue.
Cincinnati, OH 45229-3039
SPP Membership Database has New Home
The SPP membership database has recently been transitioned to an online service called MemberClicks available at
http://my.memberclicks.com/spp This service allows a member to access the member’s personal profile and edit it.
In the migration, it was discovered that 121 of the 617 members in the database had email addresses that were not functional. Email addresses in this database are used for mass mailing to the membership for important announcements. If you are an SPP member and have not received emails announcing abstract deadlines for the spring meeting in Vancouver, your email address in the database is invalid. You must email Carolyn Lane, our USCAP envoy (firstname.lastname@example.org), to update your profile.
Once in the database, you will be emailed a username and password. The landing page features a login box (pictured above) that has a link "forgot your password?" that can be clicked to retrieve your password and have it emailed to you. Thanks to Hal Pinar and Carolyn Lane for their work in the procurement of this service. The database is currently managed by Carolyn. Operational issues should directed to Mark Luquette (SPP webmaster) at
Please see our Positions
Page for the most current list of available positions.
The most current list and details concerning future
pediatric pathology meetings is available on this SPP website.
You read about it first in the SPP Newsletter! Mark you calendars for the interim meeting in 2004 in Little Rock, Arkansas!
The members of the Department of Pathology at Arkansas Children's Hospital and University of Arkansas for Medical Sciences invite you to join us for the Fall 2004 interim meeting of the Society for Pediatric Pathology, to be held in downtown Little Rock on
October 28-31, 2004. The meeting will be held at the DoubleTree hotel, conveniently located within walking distance of shops, restaurants, and downtown attractions. We have organized an exciting symposium that will focus on modern forensic diagnosis of pediatric lesions and will include discussions and counterpoint by experts in this field. The meeting will also highlight the charms of our city, which meld urban sophistication with rustic Ozark charm and Southern gentility. On Saturday we will offer an outing to Hot Springs so that you can enjoy the fall beauty of our state and the bodily comforts of our Hot Springs. We expect this to be a highly memorable, enjoyable, and educational meeting.
Meet the newest member of Council, Alexandra, enjoying
with her mom, Genevieve, and dad, Gareth Jevon
Council members who are older than Alexandra, but still
young at heart, also enjoying dinner.
Foreground (left to right) Henry Krous, Cheryl Coffin, Cindy Kaplan.
Rear (left to right) David Parham, Antonio Perez-Atayde, Denis Benjamin.
Moderators were former CCHMC fellows
including Bob Bendon and Carole Vogler who studiously approached the task...
...Kevin Bove consults Johann Johannsson...
...and John Buchino educates Ana Gomez on
whether it's a bird, or a plane, or super...
Jo Wyatt Ashmead and Jerzy Stanek(front
row) and Kelly Grove Nigro, Bev Dahms, and Mary Davis (second row) listen to
Jerzy Stanek makes a point, while Denis
Benjamin and Ray Redline wait to make theirs. Atilano Lacson takes notes.
President Derek deSa appears skeptical.
International travellers to the meeting included Ilana Ariel (left) from Israel...
...and Francesco Callea from Italy.
Archivist Bahig Shehata poses with Stephanie Young...
...and JP de
Chadarevian and John Fisher.
Pepper Dehner and Sue Simonton enjoy a
break without Bahig in the picture!
Hiro Shimada began the day Saturday by presenting an
update of neuroblastoma on behalf of the Pathology Discipline Committee of the
Children's Oncology Group.
R. J. Desnick educates and entertains the
audience during the symposium.
Greg Grabowski illustrates a point during
the superb symposium on lysosomal storage disorders that he organized.
Resident case presenters were Mana Parast
...Kelly Grove Nigro from Cleveland with
David Parham visiting her poster...
Kudakwashe Chikwava from Pittsburgh.
Csaba Galambos presents the Lotte Strauss
Sarah Johnson, Pat Kirby, Bev Dahms, and Kelly
Grove Nigro enjoy a well-deserved rest at Tall Stacks.
Joe Siebert, Amy Heerema, Raj Kapur, and Brigitte
Nixon (left to right) enjoy a night out at Tall Stacks.
Pat Kirby and a costumed greeter at Tall Stacks.
Lisa Teot, Laura Finn and Karen Thompson on board
Spirit of Jefferson.
The sun sets on Tall Stacks for 2003, but the
paddlers will return!