Fall 1998

From the Editor's Desk Award Presented at the Fall Meeting President's Message Winners of the Interim Meeting Raffle Education Committee Report Welcome to Our New Members Schedule for the Spring SPP Meeting in San Fransisco Research Committee Call for Applications Pediatric & Developmental Pathology to go to Foreign Pathologists Publications Committee Call for Nominations from the Committee on Distinctions and Awards A Meeting of Perinatal Pathologists in Toronto Positions Available Future Pediatric Pathology Meetings Interim Meeting Photos Officer/Council Members Committee Chairs & Members

It sounds as if a good time was had by all at the interim meeting in Toronto. Drs. Taylor and Becker were great hosts. As one of the folks that stayed at home to man the fort, I was grateful to receive a copy of the handout from the symposium “New Horizons in Cardiovascular Pathology." The original syllabus was printed in pink and while quite attractive, it did produce a copy of reduced readability. I hope that the Archives committee arranged for video taping the session, as was mentioned at the last annual meeting.

Houston just hasn’t been able to get it right this year. First it doesn’t rain from March until September then it decides to rain 14 inches in 24 hours. Flooding everywhere, thanks to Tropical Storm Frances. I haven’t lived through a hurricane in Houston yet, but if that’s what a tropical storm is like, I’m not sure I want to. Now we won’t even get into how the Astros and Rockets did in the playoffs this year. As they say there is always tomorrow.

The Gordon F. Vawter award for trainees was presented to Maria Parizhskaya MD, University of Pittsburgh School of Medicine and Children’s Hospital of Pittsburgh, for her poster presentation entitled “Hemophagocytic Syndrome Presenting as Acute Hepatic Failure in the Infant: Clinical Overlap with Neonatal Hemochromatosis.”

Our thanks to Larry and Edna Becker and Glenn and Anne Taylor for hosting the interim meeting in Toronto from September 25-27. The meeting was both an academic and social “success” with excellent platform and poster presentations and a superb symposium, “New Horizons in Cardiovascular Pathobiology.” Participants also enjoyed a bus tour of Toronto and a banquet in the “Bell Great Hall” of the Hockey Hall of Fame. Hockey fans including Bill Donnelly, Derek deSa, Blair Carpenter, Jim Dimmick, and others were observed paying homage to the Stanley Cup which is housed in the hall. A raffle of books and other items donated by SPP members and organized by Edith Hawkins (and others) was held during the banquet and raised over $2,000.00 for our Young Investigators Award. Participants also had the opportunity to meet or renew acquaintances with Dr. Kurt Aterman of Halifax, Nova Scotia, one of the founders of the Pediatric Pathology Club (a picture of Dr. Aterman, along with others attending the meeting is available on our webpage at http://path.upmc.edu/spp/mtg-evnt/meeting.htm).

Meeting Dr. Aterman for the first time and visiting with some of our senior society members, including Daria Haust and Harvey Rosenberg, rekindled an interest in a project I had been thinking about for the past 5 years; namely, an “Oral and Video History” of the Society. This project would involve interviews with some of our more “experienced” members, both those retired and those still working. The format would involve a video-taped and audio-recorded interview between one (or two) of our “early” society members and another possibly “younger” member who would introduce the interviewee and ask a few “basic” questions (e.g., background in medicine, involvement with the society, recollection of early society activities, remembrances of their mentors, etc.). The interviews would last 1-2 hours and a transcript of each session would be prepared and indexed. The video and audio recordings could be made available to participants and other society members and might be used at some future time in preparation of a history of the Society.

We are hoping that the first set of 8-10 interviews could take place during the March 1999 SPP and USCAP meeting in San Francisco. Subsequent interviews could be held at the Providence, RI interim meeting in the fall of 1999, the spring 2000 SPP and USCAP meeting in New Orleans and the fall 2000 interim meeting in Vancouver. We are assembling a list of Society members to be interviewed and are hopeful that these members will be able to attend these meetings and participate in the interviews. If you have suggestions as to whom we should include beyond founding members, past presidents and secretaries, please let me know (my email is Jstocker@USUHS.mil).

I must, with some embarrassment, correct an omission in the last president’s letter. In congratulating the editors of our “new” publication, Developmental and Pediatric Pathology, I failed to include James Dimmick, MD and Don B. Singer, MD, the editors of Perspectives in Pediatric Pathology which is an integral part of the journal and whose articles will also be published in a separate volume to be distributed to Society members.

At the interim meeting, the second SPP raffle for the purpose of raising money toward the Young Investigator’s Award was great fun and quite successful. We raised over $2,000 (it would have been even more if black market connections for the exchange of Canadian dollars into American had been available) and had even more prizes than last year thanks to the generosity of the donors. Faisal Qureshi won first choice and promptly made off to a chorus of “Boos” with the two volume edition of Keibel & Mall, Human Embryology, 1912, donated by Bruce Beckwith. The remaining winners are described in no particular order. John Buchino, who was not even at the meeting but had purchased tickets, chose the four books by Frank Gonzalez-Cruzi; Cindy Kaplan picked the new volume of Pediatric Tumors by Tom Stocker and Fred Askin (this was a late offering by Tom and Fred and was not in the initial advertisement); Susan Simonton picked the Atlas of Pediatric Gastrointestinal Disease donated by Milton Finegold and Edith Hawkins; Derek deSa chose the art work by Claire Langston’s daughter, Rebecca; Wes Tyson gave his ticket to his wife, Sue, who chose the lovely necklace made by Lila Penchansky (another late but gratefully accepted offering); and David Parham chose the Color Atlas of Gross Placental Pathology by Cindy Kaplan. One additional winner (whose name has vanished into thin air ) chose the AFIP volume on Systemic Pathology of HIV Infection and AIDS in Children donated by Edwina Popek, with multiple authors from the society. Thanks to everyone who donated and/or bought tickets.

The education committee received the reports from each of its four subcommittees. Input from non-committee members on any of the committee issues presented here would be gladly received.

Workshop/symposium subcommittee: The symposium and workshops for the spring meeting are described elsewhere in this newsletter. The education committee plans, in conjunction with the publications committee, to place handouts and representative slides from the symposium and completed workshops on the SPP website following the spring meeting.

Abstract subcommittee: The abstract subcommittee faces a dual-edged sword, too few abstracts for the fall meeting and too many for the spring meeting. The sword is further sharpened by complaints from members whose abstracts are rejected. Currently, abstracts are “blinded” to the reviewers (i.e. stripped of names and hospital affiliations). After a somewhat heated discussion the committee voted to continue this “blinding.” The committee reviewed the criteria used for evaluating abstracts and these criteria will be included with the “call for abstracts” in the future. The possibility of rotating posters during the spring meeting to allow the acceptance of more abstracts and the impact this would have on the poster discussion sessions was discussed. A poll of members addressing this possibility will be included in this spring’s meeting evaluation form. The work of this subcommittee is difficult and its members are to be commended.

CME subcommittee: The SPP is due for CME reaccreditation in the fall of 1999. The paperwork required to maintain our CME accreditation continues to grow over the years. Wes Tyson and the members of his subcommittee deserve our support and thanks for their continued hard work.

Extramural subcommittee: This newly created subcommittee is charged with exploring ways to increase the role the SPP plays in pediatric pathology education outside our society meetings. Increased interaction with the ASCP and possible roles (CME, website postings, etc.) in the pathology component of the newly merged CCG/POG/IRS/etc. are being explored. SPP members involved with organizations who see a potential role for SPP educational support to that organization should contact Vijay Joshi, extramural subcommittee chairperson or Henry Krous, education committee chairperson.

Welcome to the new members, which were voted on at the Council meeting.

Regular

Govind Bhagat, New York, NY
David F. Carpentieri, Philadelphia, PA
Megan K. Dishop, Lexington, KY
Wendy M. Gunther, Memphis, TN
Robert J. Krum, Portland, OR
Maureen J. O’Sullivan, St. Louis, MO
Heather Prashner, Houston, TX
Anna Elizabeth Sienko, Oklahoma City, OK
Jerry L. Simmons, Sioux Falls, SD
James F. Southern, Brookline, MA
Laura G. Sullivan, Winter Park, FL
Andre Jean Talleyrand, Newark, NJ
Puay Eng Tan, Boston, MA
Dafydd G. Thomas, Syracuse, NY

Grace E. Kim, Dallas, TX
Catherine A. Pye, South Burlington, VT
Christine A. Reyes, Houston, TX
Robert Yost, Cincinnati, OH

Anthony John Bourne, South Adelaide Australia
Shiu-Fen K. Huang, Tiapzi, Taiwan
Teck Yee Khong, North Adelaide, Australia
Jill Lipsett, North Adelaide, Australia
Patricia G. Ontiveros-Nevares, Mexico
Vivienne Heath Tobias, Sydney, Australia

Symposium on Hereditary Renal Disease
Moderator: Jay Bernstein, MD, William Beaumont Hospital, Royal Oak, Michigan

Renal Cystic Disease: Lisa M. Guay-Woodford, MD, Univ. of Alabama

Objectives:
1. Discuss the clinical-pathologic correlations in polycystic kidney disease.
2. Discuss the clinico-pathologic and genetic correlations in PKD.
3. Provide an overview of the recent molecular genetic advances in PKD research and their implications for disease pathogenesis.

Renal Involvement in Tuberous Sclerosis: Elizabeth P. Henske, MD, Fox Chase Cancer Center, Philadelphia

Objectives:

1. Describe the spectrum of renal disease in tuberous sclerosis, including cysts, benign angiomyolipomas, malignant angiomyo-lipomas, and renal cell carcinomas.
2. Describe the genetic mechanisms leading to renal disease in tuberous sclerosis
3. Describe the individual roles of the TSC1, TSC2, and PKD1 genes in tuberous sclerosis renal disease.

Objectives:

1. Provide current information on the molecular architecture of basement membranes, with a focus on type IV collagen.
2. Discuss the clinical and pathologic consequences of mutations in genes encoding type IV collagen chains.
3. Present an approach to differential diagnosis of inherited glomerular basement membrane diseases.

Objectives:

1. Describe the clinical and pathological aspects of hereditary tubulointerstitial nephritis, with special emphasis on juvenile nephronophthisis.
2. Provide an update on the recent genetic aspects of tubulointerstitial nephropathy.
3. Demonstrate the pattern of expression of the NPHP1 gene mutated in familial juvenile nephronophthisis.

Objectives:
1. Classify the causes of nephrotic syndrome presenting in the first three months of life.
2. Define the clinical, histopathologic, and molecular features of congenital nephrotic syndrome, Finnish type (CNF).
3. Define the clinical, histopathologic, and molecular features of the Denys-Drash syndrome (DDS).

This workshop aims to provide pathologists and pathology residents with an integrated clinical, radiographic, and histologic approach to the differential diagnosis of neoplastic and non-neoplastic bone lesions occurring in pediatric patients, with special emphasis on benign processes. Evaluation of skeletal lesions traditionally has included open biopsy to establish a diagnosis prior to definitive treatment. With the development of improved radiographic techniques for localizing these lesions, core biopsy (CB) and fine needle aspiration biopsy (FNAB) are assuming increasingly important diagnostic roles. This is particularly true in light of the trend towards less invasive, more cost effective procedures for diagnosis. In many instances, CB or FNAB allows accurate diagnosis of primary or metastatic bone lesions, thereby obviating the need for a more invasive and significantly more expensive diagnostic procedure. Moreover, even when definitive diagnosis is not possible, CB or FNAB can help guide further diagnostic and therapeutic planning. Participants are introduced to a variety of benign and malignant lesions, utilizing an integrated, multimodal approach which includes correlation of clinical history, radiographic studies, histologic sections, and where appropriate, Papanicolaou and Diff-Quik^TM stained cytologic preparations. The problem solving approach to developing a differential diagnosis is emphasized.

Objectives:

1. Recognize histologic and, where appropriate, cytologic features of neoplastic and non-neoplastic bone lesions occurring in the pediatric population.
2. Correlate the histologic features of neoplastic and non-neoplastic bone lesions with the clinical, radiographic and, where appropriate, cytologic findings.
3. Develop a differential diagnosis of bone lesions utilizing this integrated approach.

Changes in prenatal diagnosis and intervention have brought challenges to pediatric pathologists, who have had to become fetal pathologists. In this workshop, we will highlight our experience in making this conversion. We will provide an update of prenatal imaging techniques used to diagnose congenital malformations. We will then discuss techniques of gross autopsy examination that aid in dealing with tissues that, in addition to being malformed, are also very small, incompletely developed, disrupted, or autolyzed. Normal histologic findings, which, in the young fetus, can differ substantially from the newborn, will be demonstrated for particular gestational ages. A number of ancillary techniques, including photography, morphometry, radiography, flow cytometry, and karyotyping, will be discussed. The operation of a fetal autopsy service will be described. Reference materials and sample protocols will be provided.

Objectives:

1. Develop a systematic approach to the practice of fetal pathology.
2. Apply ancillary techniques to fetal pathology (e.g. morphometry, imaging, genetics, microbiology, molecular biology).
3. Define the role of the fetal pathologist, including establishing and operating a fetal pathology service.

2ND YEAR WORKSHOPS

This workshop is designed to familiarize pediatric pathologists with various aspects of fine needle aspiration. The course includes demonstration of various fine needle aspiration techniques, discussion on methods of controlling patients including the use of sedatives and anesthetic agents, and comparison of specimen handling techniques for optimal yield of information. Examples of both benign and malignant lesions encountered will be given as well as discussion of the differential diagnosis. Cytologic/histologic correlations will be utilized whenever possible.

Objectives:

1. Familiarize pathologists on the indications, advantages and disadvantages of fine-needle aspiration cytology biopsy in pediatrics.
2. Discuss methods of controlling the patient including the use of sedatives and anesthetic agents.
3. Discuss techniques to obtain and handle the specimens.

After reviewing histochemical and immunohistochemical techniques useful in the evaluation of muscle biopsies, this workshop concentrates on aspects of diagnostic muscle pathology which have been impacted by new technologies. Topics covered include: Embryology of muscle including the role of myogenic genes Congenital myopathies, such as the centronuclear myopathies, infantile myofibrillar myopathy and congenital muscle fiber type disproportion. New stains available for muscle biopsies, including immunohistochemical markers of sarcoplasm-related cytoskeletal proteins such as dystrophin, the sarcoglycans, and merosin.

The distinction between primary neurogenic atrophy with secondary myopathic changes and primary myopathy with secondary neurogenic changes.

Objectives:

1. Understand the strengths and pitfalls of the various histochemical and immunohistochemical stains used in muscle pathology.
2. Become acquainted with the clinical and histopathologic features of the congenital myopathies.
3. Be better able to distinguish between primary vs. secondary neurogenic and myopathic changes.

3RD AND FINAL YEAR WORKSHOPS

In Brain Tumors of Childhood: The Good, the Bad and the Ugly, we use 6 illustrative cases as springboards for further discussion. Much of the workshop is devoted to avoiding the (over)diagnosis of malignancy in some common, and not so common benign childhood brain tumors. We try to clarify some of the confusion surrounding primitive central nervous system tumors, including medulloblastoma and its evil stepsister, the atypical teratoid/rhabdoid tumor. We finish by considering some of the pitfalls in making big diagnoses on small (actually, minute) amounts of tissue, using the pineal region as prototype. Plenty of time is allotted for questions and discussion of these fascinating and informative cases.

Objectives: After attending this workshop, the participant should:

1. Be familiar with a variety of benign childhood brain tumors which may be mistaken for similar appearing, but more biologically aggressive lesions.
2. Appreciate histopathologic variations seen within primitive central nervous system tumors of childhood and their prognostic significance.
3. Be aware of diagnostic pitfalls encountered when working with limited amounts of tissue derived from central nervous system tumors.

After an introduction to the technical aspects of handling bone marrow aspirate and biopsy material this workshop focuses on three diagnostic dilemmas in hematopathology: parvovirus infections, metastatic tumors, and acute megakaryoblastic leukemia. The discussion of parvovirus infections includes clinical highlights, peripheral blood and bone marrow morphology, and aspects of the molecular biologic diagnosis. Metastatic tumors are divided in an unorthodox manner: the frequent, the rare and those that simulate other malignancies. Ancillary techniques useful in the diagnosis of bone marrow metastases are highlighted. The unique clinical and morphologic aspects of acute megakaryoblastic leukemia are broadly illustrated along with tips on the use of ancillary techniques in making this often difficult diagnosis.

Objectives:

1. Learn to recognize parvovirus infection in the fetus, new born, normal and immune-suppressed children using morphological, immunohistochemical and molecular techniques.
2. Learn to recognize the different pediatric tumors that metastasize to bone marrow in aspirate and biopsy material.
3. Learn to diagnose acute megakaryocytic leukemia in bone marrow and distinguish it from other malignancies that may simulate its morphology.

YOUNG INVESTIGATOR RESEARCH GRANT

Application Process: To obtain an application contact the SPP Executive Office, Degnon Associates, Inc., 6728 Old McLean Village Drive, McLean, VA 22101, 703/556-9222 or FAX 703/556-8729, or E-Mail socpedpath@degnon.org. The guidelines for the award are as follows:

Goals:

1. To foster research within the SPP by providing seed money to young investigators in pediatric pathology.
2. To find a pilot project following which the investigator can apply to other granting agencies.

Purpose of Funding: The funds are to be used to facilitate basic or applied research of a young investigator in the field of pediatric pathology. The following are appropriate expenditures: capital equipment, reagents and supplies, travel to meeting to present data, and salary supplements. Other appropriate expenditures include: fees required to purchase specific services such as an electron microscope, scanning EM, etc., or other specified techniques or test. Animal care costs are also considered appropriate.

Amount of Award: There will be (1) award up to a maximum of $10,000. This is a nonrenewable, one-term award.

Who May Apply:

• All applicants with a MD, MD/PhD, or DO degree.
• Residents or fellows, full-time, in an accredited pathology training program.
• Faculty and staff who have been in Pediatric Pathology less than 5 years and are regular members.
• The applicant must be a member of the SPP or sponsored by a SPP member.

Selection Process: Completed applications must be received by the Chair of the Research Committee no later than March 1, 1999. They will be reviewed by the Research Committee of the SPP, and awards will be announced at the March SPP meeting. Award funding will begin on July 1, 1999.

Application: Please submit a completed application form to Chairman of the Research Committee, David M. Parham, MD, Chief of Pediatric Pathology, Arkansas Children’s Hospital, 800 Marshall Street, Little Rock, AR 72202-3591. Be sure to fill out all segments. In addition, an approval from either Institutional Review Board (if human subjects are involved) and/or Animal Care Committee should be included as appropriate.

Expectations: It is expected that the recipient of this award will present the results of the research at the meeting of the Society for Pediatric Pathology and submit one or more manuscripts to Pediatric and Development Pathology for consideration

The Society for Pediatric Pathology and Children’s Hospital Medical Center, Cincinnati Ohio, has established the A. James McAdams Short Term Study Stipend. The purpose is to honor A. James McAdams, M.D. by supporting and promoting opportunities for any member of the SPP or fellow in training in an accredited program in pediatric pathology and sponsored by a member of the SPP to learn specific investigative techniques not available at their institution. This opportunity may be used to learn and develop new research skills related to either clinical or laboratory investigations from experts with the Society or outside the Society. One annual award of up to $2,000 will be made to support travel and living expenses of a pediatric pathologist for study for up to one month. The application request should include the following:

1. An abbreviated CV including name and current position, training, and/or professional experience, and brief description of current research interests and activities.
2. A letter from the applicant’s chief in support of the training experience.
3. A letter from the chief or laboratory director at the institution that the applicant wants to visit indicating approval of the proposed training experience.
4. A brief description (less than one-half typed page) of the type of training to be pursued and how it will promote the applicant’s investigative career in pediatric pathology.

Interested parties should contact: David M. Parham, M.D., Chair, SPP Research Committee, Chief of Pediatric Pathology, Arkansas Children’s Hospital, 800 Marshall Street, Little Rock AR 72202-3591.

Under the guidance of Dr. Alba Greco, our Pediatric & Developmental Pathology journal will be sent to 25 pathologists in developing countries, courtesy of the Society. If other members of the Society have journals or books that they wish to donate, please contact either Dr. Greco or the SPP central office.

The Publications Committee expanded its meeting in Toronto to include representatives from Springer-Verlag, who provided valuable input about journal sales and marketing. They said the journal was on track and doing as expected for the first year. Society subscriptions comprise the bulk of the sales, and we need to continue to encourage our libraries to subscribe to Pediatric and Developmental Pathology. If you do not know if your library subscribes to the journal, call them today and find out. If they do not, it is time to request that they do. Springer-Verlag is continuing to aggressively market the journal to the libraries. You will be receiving promotional material from Springer-Verlag with the 1999 January/February issue. The promotional material, called a carrier sheet, contains a checklist about how you value and use your journal. When you get this, please fill it out and send it to your institutional libraries. For those of you wondering about indexing for Pediatric and Developmental Pathology, it’s pending. Review by the National Library of Medicine will occur either in the fall or winter, so we will keep you posted.

VISIT THE WEBSITE! (http://path.upmc.edu/spp/). (Webmaster's note: The current website is http://www.spponline.org/.) If you have any information to be placed on the Website (meeting announcements, educational programs, etc.), send it to Dr. Paul Dickman and he can put in on-line for you. You can send it to Paul as an attachment via e-mail or by non-electronic means. It’s a great way to get the word out about an upcoming event. Items such as registration forms may be printed off and mailed - no need to find it under the pile on your desk. Discussions are underway with the Education Committee to add educational items, such as short course and symposium handouts (with authors’ permission), to the Website. So, take some time to look and see what is available.

Lotte Strauss Prize

The Committee on Distinctions and Awards wishes to remind members of the Society to submit nominees for the Lotte Strauss Award. The Dr. Lotte Strauss award will recognize meritorious work by an individual 40 years of age or younger in a subject germane to pediatric pathology, published or accepted for publication during 1998. The winner will receive a $1000 cash prize and round trip airfare to the 1999 Annual Meeting of the Society for Pediatric Pathology where the work will be presented in a special platform presentation. Nomination requires submission of five copies of the completed paper, a supportive letter from the nominee’s sponsor, and five copies of the nominee’s curriculum vitae. These should be mailed to: David Witte MD, Chairperson, Committee on Distinctions and Awards, Department of Pathology, Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati Ohio 45229. Deadline for receipt of complete nomination package is December 1, 1998.

Harry B. Neustein Memorial Award

The Harry B. Neustein Memorial Award was generously established by the Neustein family to recognize the significant contributions made by Dr. Harry Neustein to pediatric pathology. Traditionally this award was presented to abstracts to recognize meritorious work involving electron microscopy. During more recent times there have been very few abstracts submitted for this award in part due to decreasing utilization of electron microscopy in pathology studies. Therefore in an effort to revitalize the importance of this award in the Society, the Committee on Distinctions and Awards during the past year has revised the criteria for the award with approval of Council. The newly expanded criteria for this award now includes abstracts for studies utilizing electron microscopy, new methodological advances in molecular technology or immunohistochemical techniques or development of other innovative technological advances that pertain to pediatric pathology. It is hoped that expanding the scope of this award will renew interest in it and consequently reestablish the purpose intended by the Neustein family to honor Dr. Harry Neustein.

There was a meeting of perinatal pathologists held the day before the interim SPP meeting organized by Drs. Bob Bendon, Ray Redline, Cynthia Kaplan, Steve Lewis, and Kurt Benirschke. The day started with the presentation of abstracts, then broke into two smaller discussion groups; first on practice and research, then on education and a collaborative autopsy project. The conclusion was a general business meeting which resolved to ask the SPP council to establish a Perinatal Division of the SPP. This group would work with the SPP to accomplish specific goals for which each of the discussion sessions presented some initial ideas. The first research aim was to create a database of NIH style biographies to be used by the SPP, and also with permission given to NICHD and other potential collaborators. Planning would begin on a virtual database of specimen resources. The education group decided that one must straighten your own house first, and chose to tackle a topic by topic review of diagnostic categories within placental pathology. The practice committee identified some of the key problems within perinatal pathology, and chose a few to tackle. The autopsy collaboration on oligohydramnios cases with small bladder, large (or normal) kidneys, began with cases submitted to Dr. Bendon, which are being entered into Filemaker Pro database. This is the initial step in a collaboration which will give more people access to case material for self education and research.

Also resolved was to ask the board of the Study Group for Complications of Perinatal Care for permission to subsume its goals, functions and funds. In return, we would offer clinical members one free year membership in the SPP. Remaining funds would be used to establish an award in honor of Dr. Kurt Benirschke and Dr. Molly Valdes Dapena (pending their permission) for the best perinatal pathology presentation at the SPP meeting.

The Perinatal Division will meet at least informally at the San Francisco meeting and will plan a meeting the day before the Rhode Island SPP interim meeting. To make this new division a permanent organization for perinatal pathology is still going to take a lot of effort. The enthusiasm and support from many members of the SPP, including President Tom Stocker and ex-president Jim Dimmick, were very encouraging. The Perinatal Division is launched. Anyone desiring to crew the ship, or even to just obtain passage, may sign on. Contract Robert Bendon, M.D., Kosair Children’s Hospital, P.O. Box 35070, Louisville, KY 40232-5070, phone (502) 629-7900, FAX (502) 629-7906, E-mail bendon@ix.netcom.com

Positions Available

The Division of Pathology at Children’s Hospital Medical Center, Cincinnati Ohio seeks a qualified individual as Director of Clinical Laboratory Medicine with faculty appointment in the Department of Pathology and Pediatrics, University of Cincinnati College of Medicine. The successful candidate should provide the leadership to direct the comprehensive clinical laboratory services for the inpatient and outpatient needs at CHMC, promote the ongoing efforts in outreach testing programs, and provide the necessary academic environment and laboratory support for the development of clinical treatment or research programs within the institution. The Clinical Laboratories offer comprehensive clinical pathology services and perform more than 1,000,000 clinical tests annually.

Candidates should be have an MD or MD/PhD degree, and be Board-Certified in Clinical Pathology. Academic rank will be determined by candidate’s credentials and experience. Children’s Hospital Medical Center is an Affirmative Action/Equal Opportunity Institution. Women and minorities are encouraged to apply.

Submit Inquires To: David Witte MD, Director, Division of Pathology, Children’s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229; Phone: (513) 636-4261

The Children’s Hospital of Denver and the Department of Pathology of the University of Colorado School of Medicine are conducting a joint search for faculty members with MD or MD/PhD degrees who are board certified or eligible in AP/CP or AP with subspecialty training in Pediatric Pathology. A strong commitment to service, teaching and research is necessary. Send correspondence (including CV and list of three references) to: Joel E. Haas, MD, Chair Designate, TCH Department of Pathology, 3861 Woodlake Drive, Bloomfield Hills, MI 48304

The Children’s Hospital and the University of Colorado Health Sciences Center are committed to equal opportunity and affirmative action.

Magee-Womens Hospital and the University of Pittsburgh Department of Pathology are seeking an experienced academic Perinatal Pathologist at the Associate Professor or Professor rank to assume the position of Director of Perinatal & Developmental Pathology, reporting to the Chief of Pathology at Magee-Womens Hospital. Faculty of the Department of Pathology of the University of Pittsburgh with a special interest in Obstetric, Gynecologic, Reproductive and Perinatal Pathology are assigned to Magee-Womens Hospital Department of Pathology. Magee-Womens Hospital and its Womencare Centers and Satellites provide the major tertiary Womencare services for the University of Pittsburgh Medical Center and it is a member of the Tri-State Health System - a regional Integrated Delivery System coordinated by the University of Pittsburgh Medical Center.

Clinical services include over 9,000 deliveries per year, a strong genetics counseling program, including early pregnancy loss, supported by university faculty specialists in maternal-fetal-medicine, neonatology, ultrasound and reproductive genetics. The Director of Perinatal & Developmental Pathology is required to have several years of “hands on” experience in the full range of diagnostic perinatal pathology including placental pathology, pathology of early pregnancy loss and fetal neonatal pathology. This is required in order to lead an academic diagnostic perinatal pathology service in a multi disciplinary academic setting that provided for close interdisciplinary collaboration with both pathologists and clinicians in the above mentioned clinical service areas. The director should also aim to develop a funded research program in perinatal pathology related areas. Laboratory space and set-up funds can be allocated as necessary.

Pediatric Neuropathology expertise is available through the Department of Pathology at the University of Pittsburgh. Molecular Diagnostics, Molecular Genetics, Flow Cytometry, and other state-of-the-art technology is accessible through the Department of Pathology of the University of Pittsburgh. With system integration initiatives opportunities exist to expand a regional perinatal pathology serviced.

The position is available October 5, 1998. Applications should be forwarded to Trevor Macpherson,MBChB, FRCOG, Chief of Pathology, Magee-Women's Hospital and Professor of Pathology University of Pittsburgh School of Medicine, 300 Halket Street, Pittsburgh PA 15213 or phone (412) 641-4655.

The University of Pittsburgh is an equal opportunity employer.

The Department of Pathology and Laboratory Medicine at the Indiana University School of Medicine in Indianapolis, Indiana is seeking an AP board certified pathologist with special expertise in pediatric pathology to fill a tenure track position in its Division of Anatomic Pathology at either the Associate of Full Professor level and to serve as the Director of Pediatric Pathology at the James Whitcomb Riley Hospital for Children (JWRHC) on the campus of IUMC. The successful candidate will have strong diagnostic skills and a record of scholarly activities; prior administrative experienced is highly desirable. The candidate will be responsible for directing the service, educational, and research programs of the Division of Pediatric pathology which currently has two full-time faculty members. The JWRHC is one of the primary teaching hospitals at IUMC and is the only dedicated pediatric hospital in Indiana. It accessions approximately 3,800 surgical specimens and performs 100 autopsies per year. The pathology laboratories at IUMC are a resource that is available for service and research, with particularly strong components in immunohistochemistry, electron microscopy, and molecular diagnostics.

Interested candidates should submit a curriculum vitae and the names of three references to: Thomas M. Ulbright, M.D., Director of Anatomic Pathology, Indiana University Hospital, Room 3465, 550 North University Boulevard, Indianapolis, IN 46202-5280. Indiana University is an Equal Opportunity/Affirmative Action Employer.

The Department of Pathology at the University of Utah has an opening in the Division of Pediatric Pathology at Primary Children’s Medical Center, for a board-certified or board-eligible, AP or AP/CP pathologist. A subspecialty interest in pediatric surgical pathology and/or pediatric transfusion medicine is highly desirable. The position includes service and teaching responsibilities in pediatric pathology at the Assistant or Associate Professor level (clinical or tenure track). The successful candidate will have strong diagnostic skills and an interest in teaching and scholarly activities. Interested candidates should send a curriculum vitae and names of three references to: Cheryl M. Coffin, MD, Head, Division of Pediatric Pathology, Primary Children’s Medical Center, 100 North Medical Drive, Salt Lake City, UT 84113. The University of Utah is an equal opportunity/affirmative action employer and encourages applications from women and minorities.

SPP Meetings

1999 Annual Meeting
March 20-21
San Francisco, CA
Symposium: Renal Disease

1999 Interim Meeting
September 24-25
Providence, RI

International Meetings

6th International Workshop on Fetal Genetic Pathology
March 14-18, 1999
Dead Sea, Isreal
For additional information: Tel: (972 3) 5175150;
Fax: (972 3) 5175155; e-mail: trgt@netvision.net.il

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See SPP Information -- Officers, Committees and National Office

See SPP Information -- Officers, Committees and National Office