Winter 1999

From the Editor's Desk
Edwina J. Popek, DO

Now that the holidays are over, we can all relax and regroup for the final year of the millennium. With the birth of the octuplets, the Holiday season brought quite a bit of publicity to Texas Children’s Hospital and St. Luke’s Episcopal Hospital; most of it has been good. You can’t imagine how difficult it is to get around the Texas Medical Center when there are huge media trucks from 6 or so major Networks, transmitting live via satellite right out your back door. My part—I got to do the placentas. But don’t look for me on any newscast about the findings, the only one interested enough to call me was the Chief of Neonatology. We will probably have several more months of excitement until all babies are home. Who ever said that Pathologists were boring, hasn’t been to an international meeting with us. Check out the travels of Society members in this newsletter. I am looking forward to the meeting in San Francisco, it’s a trip down memory lane back to my old residency days, plus it’s such a great city. You don’t even feel the little earth quakes after a while—only the bigger ones get your attention. This notice appeared on Page 1 of the weekly paper in Clermont, FA: “If you find mistakes in this publication, please consider that they are there for a purpose. We try to publish something for everyone, and some people are always looking for mistakes.”

President's Message
J. Thomas Stocker, MD

As I have heard a number of former SPP presidents comment, the year of their presidency seems to fly by. And I certainly am no exception. The Boston meeting last March at which I was deeply honored to be installed as president seems like only a few short months ago, but many important events have occurred in that time. Thanks to the efforts of our journal’s editors and coeditors, Drs. Benjamin, Berry, Garvin, Hicks, Qualman, Singer and Dimmick, Pediatric and Developmental Pathology has completed its first year of publication and has received the “blessings” of the National Library of Medicine and thus will be fully indexed from its first issue on a continuing basis. The quality of papers received and published has been exceptional and the publishers, Springer-Verlag, have indicated a willingness to actively promote the journal through extensive marketing and a commitment to additional pages for the journal. And within the coming year we look forward to the publication of the collected “perspectives” articles from the first year of the journal in a "new" Perspectives in Pediatric Pathology.

This past year has also seen a remarkable growth in SPP member’s interest in perinatal and placental pathology. Under the leadership of Bob Bendon, society and other physicians involved with perinatal issues organized an “informal” session prior to last September’s Toronto meeting to present scientific studies and to discuss how they might be more actively integrated into the Society’s functions. We are looking forward to their participation in the educational, organizational and publication activities of the Society.

The audio-visual history project I mentioned in my previous letter will be starting at the March meeting in San Francisco with the interviewing of a number of our former presidents and senior members. Over the period of the next two to three years, we hope to record on audio and video tape, the recollections of many of our members of the history of our society and of pediatric pathology. These interviews will be available in the future as tapes and as transcriptions of those tapes for use by our members.

On a personal note, I would like to thank our new secretary-treasurer, Deb Perry for all of her help this year. She has handled extraordinarily well the myriad of details necessary to run this organization. My thanks also to our recent past-president, Jim Dimmick and to our incoming president, Joe Rutledge for their counsel and support and, to all of our committee chairs and members, our editors and our office staff. This is truly an organization dependent on many dedicated people. And finally, my thanks to my family for being in Boston at the start of this year and for making this year a true joy with Rick’s wedding in August and the coming completion of his Internal Medicine residency in July, with David’s anticipated graduation from medical school in Colorado in May, and with Meg’s all-to-soon graduation from high school in June.

I plan to continue my activities with the Society with efforts to promote a continuing growth in membership in the Society and to expand the educational programs cosponsored by the Society and the Institute for Pediatric Medical Education. Thanks to all of you for a wonderful year. E-mail:

Proposed Bylaws Changes
Linda Margraf, M.D.

Proposed additions to the Bylaws are typed in bold; Proposed deletions contain a strike-through.

Article III    Council
Section 2. Number and Election
The number of Councilors of the Society shall be determined from time to time by resolution of the Society’s members. In the absence of a contrary resolution, the number of Councilors shall be fifteen (15) – fourteen (14) if the offices of Secretary and President are held by the same person and The Council shall consist of the President, Past President, President-elect, Secretary, Treasurer of the Society; the Chairpersons of the Education, Practice, Publications and Research committees; all of the Standing Committees and six (6) other members who shall be elected as at-large Councilors by a majority vote of the Regular Members in attendance at the annual meeting of the Society. All nominees shall be members in good standing.

Article VI
Section 5.   Nominating Committee
(a). Composition. This committee shall consist of the President-elect, who will be the Chairperson, the two (2) most recent Past Presidents, and three (3) members with staggered terms of three (3) years each, one of whom shall be appointed annually by the President. In the Society’s first two years of existence, the President may appoint persons from among the regular membership to this committee to fill the otherwise vacant Past President’s slots.

Article VI
Section 7.   Education Committee
(a). Composition.
(line 9)....evaluation cycle. The Chairperson shall be a member of the Council and of the Liaison Committee and an ex-officio member of the Distinctions and Awards Committee.

Article VI
Section 11. Practice Committee.
(a). Composition. This committee shall consist of a Chairperson, whose term shall be three years and of six (6) nine (9) members with staggered terms of three (3) years each. Two Three members shall be appointed annually by the President. The Chairperson shall be a member of the Council and of the Liaison Committee.

Article VI
Section 12.   Publications Committee.
(a). Composition. This committee shall consist of a Chairperson, whose term shall be three years and of four members with staggered terms of two (2) three (3) years each. Two Members shall be appointed annually by the President as necessary. Additionally, the President shall appoint ex-officio members to the committee consisting of the editors of the Society newsletter, Worldwide Web Home page and journal(s) under editorial control of the Society. All ex-officio members shall be granted the full rights and voting privileges accorded to regular members. The Chairperson shall be a member of Council.

Any or all members of the committee may be editors or members of the editorial boards of Society related publications with approval of Council.

Article VI
Section 13. Research Committee.
(a). Composition. This committee shall consist of..... The Chairperson shall be a member of the Council and of the Liaison Committee.

Article VI
Section 14. Liaison Committee.
(a) Composition. The Secretary shall be the Chairperson and members shall be the chairs of the Education, Research and Practice committees and three (3) additional members with staggered terms of three (3) years each. Members shall be appointed by the President as necessary.

1999 Matching Plan for Fellowship
Milton J. Finegold, M.D., Chairman

Seven programs and 5 candidates participated in the first NRMP for fellowships in Pediatric Pathology and the results were announced on January 6, 1999. There are 22 ACGME-accredited programs and several of them had made commitments to candidates for July 1, 1999 before Dr. Henry Krous’ efforts were implemented. Some programs have already committed places for 2000. The NRMP staff have asked the SPP to review this year’s activity and to consider its position on future use of the match. They have indicated that an earlier date for the match would be possible, if that would encourage participation. The Fellowship Committee that Dr. Bill Bradford chaired and Dr. Bill Donnelly contributed mightily to in gaining ACGME approval for the Fellowships has been reactivated by President-elect Rutledge and will begin the suggested review at the SPP Annual Meeting in March. Its members include Drs. Jim Dimmick, Jerry Garvin, Henry Krous, Tony Perez-Atayade, Van Savell, and Glenn Taylor. All SPP members are asked to share your views about the match with us in time for the March meeting.

Report from the Publications Committee
Beverly Rogers, M.D., Chairperson

The year 1998 ended with the stupendous news that Pediatric and Developmental Pathology has been indexed by the National Library of Medicine. The journal will be listed in Index Medicus and Medline, and the indexing will be retroactive to the first issue. We need to acknowledge the hard work and fortitude of Dr. Denis Benjamin, editor-in-chief of PDP, Dr. Jim Dimmick and Dr. Don Singer, editors of Perspectives in Pediatric Pathology, Mr. Degnon from the central office, Ms. Annie Cimino and other representatives from our publisher Springer-Verlag, and all those who submitted and reviewed articles for these first issues. We are now into volume 2, with new additions to the editorial board. We want to thank all of those who are rotating off the editorial board, and welcome the new members.

For those of you who follow the world financial reports, you may have heard that Springer-Verlag has assumed a partnership with Bertelsmann AG, a publishing firm with a focus on electronic publishing and strong distribution channels. Springer-Verlag expects that little will change from the standpoint of their management structure, staff, or operations.

We are making changes to the by-laws this year; these are printed in the newsletter. These changes are meant simply to clarify which members of the Publications Committee are voting members, and to stagger the terms of regular members in the same manner as other SPP committees. The Publications Committee has always had the editors of the SPP publications as ex-officio member and their voting status has never been defined. We would like to formalize that they are voting members of the Committee.

The Web Site is constantly being updated, with information about meetings, registration forms, and other timely information. The address is: (Webmaster's Note: The new website is Let us know if there are other additions you would like to see.

Pediatric Pathologists Around the World, Spread the Word

The International Academy of PathologyCongress,
Nice, France, October 1998
Liliane Boccon-Gibod, M.D.

It’s hard to believe that it’s been nearly three months since the pediatric (and other) pathologists met in Nice last October. The International Pediatric Pathology Association met in concert with the International Academy of Pathology. The meeting proved to be informative and fun, and culturally rewarding for those who were able to include in their schedule the visit of the Matisse and Chagall museums. Most of the happy ones who were able to travel through the Provence after the meeting also mentionned the very special light from the Provence.

Highlights of the Scientific Program included a Short Course on Soft Tissue Tumors (L.P. Dehner, P. Thorner) and another one on Renal Tumors in Children and Adults (J.B.Beckwith and S. Storkel).They were both highly suscribed. Dr Dehner had to deal with some gremlins nested in the slide- projector, and he proved to be able to tame them with maestria. Later on in the week, there was a moment of emotion in the audience when Dr Beckwith announced that it was one of his last performances. A Symposium on Pediatric Lung was chaired by E.Cutz and T. Stocker. It was extremely well attended. The chairmen and speakers at the IPPA Companion meeting led by R. Kaschula and K. Misugi on Cholestasis in Children came from 4 different continents. The IPPA meeting was of high Scientific interest ; it welcomed the participation of French pediatric pathologists ( Dr M. Hadchouel, Dr M. Fabre) working with the team of Dr Alagille who described the syndrome which bears his name. A Slide seminar was organised, on Surgical pediatric pathology (J. Briner, L. Boccon-Gibod). We missed the presence of Jorge las Heras as a speaker at this Slide Seminar, but it was for a good cause : on the very day of the Seminar in Nice he was established in his new office of Dean of the University of Santiago de Chile by the president of Chile, Eduardo Frei. We are proud for him and for Pediatric Pathology. Fetopathology was not forgotten : J.Keeling and D. Gaillard chaired a slide Seminar on Placental and Fetal Pathology and a brilliant symposium on genetics and molecular biology in Fetopathology was led by D. Kalousek and D. Gaillard.

The Editorial Board of Pediatric and Developmental pathology met at lunch time on the Tuesday in a french provencal bistrot. Although the great news of the indexation of PDP in the Index Medicus had not yet been available to Denis Benjamin at that time, the atmosphere was excellent.

On the Wednesday the IAP Congress organized a wine and cheese party, which, thanks to Francis Jaubert, the President of the Congress, really involved wine tasting ( dozens of different wines from all the french provinces) and cheese ( also very many cheeses); As you can guess, pediatric pathologists were not the least interested in the cheese (and the wine...)

On Thursday evening, the IAP Congress held it’s gala dinner at the Hotel Negresco; at the same time, the Pediatric pathologists had their own special dinner, in a very nice but less formal setting. It was attended by over 80 pathologists and spouses who seemed pleased with the local food and the french wine. I have even been told that some of them came back on the following evening to enjoy some other local specialities.

So on the whole, the IAP and IPPA meetings were a big success. The next rendez-vous is in Japan, October 2000. Don’t miss it!

Pediatric Pathology in Panama City, Panama: November 15-20, 1998
Edwina J. Popek, D.O.

The VIII Conferencia Latinoamericana de Pathologia Pediatrica was held in conjunction with the XX Congreso CentroAmericano y del Caribe de Pediatria in Panama City at the convention center. The Sociedad Latinoamericana de Pathologic Pediatric program was organized by Dr. Moises Espino Duran, President of the VIII Lantiamerican Conference on Pediatric Pathology and Dr. Patricia Gil del Real de Cano, former pediatric pathology fellow at Texas Children’s Hospital and secretary of the Conference.

The program included presentations from members of the Society for Pediatric Pathology Drs.: Carlos Abramowsky, Maria T. Garcia de Davila, Derek de Sa, Ricardo Drut, Enid Gilbert-Barness, Julio Goldberg, Alba Greco, Carmen Gutierrez, Edith P. Hawkins, Gareth Jevon, Jorge Las Heras, Eduardo Lopez-Corella, Lila Penchansky, Edwina J. Popek, Poul Sorensen, and J. Thomas Stocker. The topics presented included aspects of gastrointestinal pathology, hepatic pathology, hematopathology, cardiac pathology and tumor pathology.

The conference was not all hard work. Thanks to the organizing committee we had the opportunity to see the historic and beautiful part of Panama City as well as the Panama Canal. A special opportunity to see “Native Panamanians” was provided by Dr. Patricia Gil del Real with a boat trip to one of the Native Indian tribes that still lives the “old fashioned way”.

Photos from VIII Conferencia Latinoamericana de Pathologia Pediatrica

Click here to see larger images of these pictures.
Panama - Photo 01 Panama - Photo 02 Panama - Photo 03
Panama - Photo 04 Panama - Photo 05 Panama - Photo 06
Panama - Photo 07 Panama - Photo 08 Panama - Photo 09
Panama - Photo 10 Panama - Photo 11 Panama - Photo 12
Panama - Photo 13 Panama - Photo 14

Metropolitan Pediatric Pathology Club
Dena M. Selby, M.D.

The Metropolitan Pediatric Pathology Club met for a Saturday afternoon/dinner meeting on October 3, 1998. SPP members present included Dr. Roma Chandra and Dr. Dena Selby from the Children’s National Medical Center, Dr. J. Thomas Stocker from the Uniformed Services Health Science Command, Dr. Elizabeth Perlman and Dr. Peter Argani from Johns Hopkins, Dr. Chen-Chih Sun for the University of Maryland, Dr. Shimareet Kumar from the National Institue of Health, Dr. Jasbir Johal from Fairfax Hospital, and Dr. Joseph Pestaner from the Office of the Chief Medical Examiner in Baltimore, MD. Dr. May Arroyo, a pathology resident from Johns Hopkins was also present.

The afternoon scientific session was very informative and educational and included case presentations of severe viral gastroenteritis, alveolar capillary dysplasia, primitive sarcoma in the abdomen (Dr. Selby); EBER stain of a cecal leiomyosarcoma in an AIDS patient, solid alveolar rhabdomyosarcoma of the urinary bladder (Dr. Kumar); hamartomatous lesion of the spleen in Williams syndrome, hepatocellular carcinoma (Dr. Stocker); possible CCAM in a teenager, cysticercosis of the brain (Dr. Chandra); metastatic squamous cell carcinoma to the liver in a 17 year old, overwhelming herpes of the liver in a 5 day old (Dr. Pestaner); lipoblastomatosis of the vulva (desmin positive), lipoblastoma of the lower leg (Dr. Perlman); splenogonadal fusion, pleuropulmonary blastoma, Ewings sarcoma metastatic to the kidney (Dr. Sun); metastatic neuroblastoma in the placenta, embryonal sarcoma of the kidney with tX,18, cellular mesoblastic nephroma (Dr. Argani). The meeting was followed by dinner at La Ferme, which proved to be a delightful evening for all.

The Metropolitan Pediatric Pathology Club was formed circa 1986. The Club meets on the second Thursday morning of each month at Children’s National Medical Center. The usual format includes a journal club from 8:30-9:30 am, followed by an informal sharing of cases. Cases include anything of interest to the presenter that might be of interest to the rest of the group. Unusual lesions, newly described lesions and “wow” cases comprise the majority of cases shown. We sit around a multiheaded scope, although an occasional Kodachrome is shown to demonstrate gross pathology. CME credit for up to 2 hours is offered for each session. Refreshments are served. Anyone interested in joining our group can call Dena Selby, M.D. at (202) 884-2051 for information on the time and place of the next meeting.

Society for Pediatric Pathology Program Summary

  FRIDAY, MARCH 19, 1999
  Registration-San Francisco Hilton, West Lounge 2:00 PM - 7:00 PM
  SATURDAY, MARCH 20, 1999
  Registration-San Francisco Hilton, West Lounge 7:30 AM - 6:00 PM
  Platform Sessions
     IA - Imperial A 8:30 AM - 10:00 AM
     IB - Imperial B 8:30 AM - 10:00 AM
  Coffee Break - Yosemite Room 10:00 AM - 10:45 AM
  Poster Presentations - Yosemite Room 8:30 AM - 5:00 PM
  Poster Discussion - Imperial B 10:45 AM - 12:15 PM
  Symposium - Imperial B 1:30 PM - 5:00 PM
  Symposium - Renal Disease
  Moderator: Jay Bernstein, William Beaumont Hospital, Royal Oak, MI

  Renal Cystic Disease
    - Lisa M. Guay-Woodford, University of Alabama, Birmingham, AL

  Renal Involvement in Tuberous Sclerosis
    - Elizabeth P. Henske, Fox Chase Cancer Center, Philadelphia, PA

  Abnormalities of the Glomerular Basement Membrane
    - Clifford E. Kashtan, University of Minnesota, Minneapolis, MN

    - Corinne Antignac, Hospital Necker - Enfants Malades, Paris, France

  Congenital Nephrotic Syndrome
    - Bernard S. Kaplan, Children’s Hospital, Philadelphia, PA

  Business Meeting - San Francisco Hilton, Imperial B 5:00 PM - 6:00 PM
  Social Hour and Banquet - San Francisco Hilton, Plaza A 7:00 PM
  SUNDAY, MARCH 21, 1999
  Registration-San Francisco Hilton, West Lounge 7:30 PM - 3:00 PM
  Plenary Session - San Francisco Hilton, Imperial B 8:30 AM - 12:30 PM
  Platform Sessions II 8:30 AM - 10:00 AM
  Coffee Break - San Francisco Hilton, Yosemite Room 10:00 AM - 10:45 AM
  Lotte Strauss Prize Presentation and Paper 10:45 AM - 11:15 AM
  Other Awards 11:15 AM - 11:30 AM
  Sidney Farber Lecture - J. Bruce Beckwith 11:30 AM - 12:30 PM
  “Life in the Gray Zone: Dealing With Uncertainty in Diagnostic Pathology”
  Poster Session - San Francisco Hilton, Yosemite 8:30 AM - 12:30 PM
Session A    1:30 PM - 3:30 PM    Yosemite A
Pediatric Bone Tumors and Tumor-Like Lesions: An Integrated Approach to Differential Diagnosis
Lisa A. Teot, M.D. and David G. Hicks, M.D., University of Rochester Medical Center, Rochester, NY

Session B    1:30 PM - 3:30 PM    Yosemite B
New Advances in Pediatric Muscle Pathology
Harvey B. Sarnat, M.D., F.R.C.P.C., Children’s Hospital and Regional Medical Center, Seattle, WA

Session C    1:30 PM - 3:30 PM    Yosemite C
Brain Tumors of Childhood: The Good, the Bad, and the Ugly
Mark L. Cohen, M.D., University Hospitals of Cleveland and Richard A. Prayson, M.D., Cleveland Clinic Foundation, Cleveland, OH

Session D    3:45 PM - 5:45 PM    Yosemite A
Congenital Malformation in the Fetus: Approaches to Examination and Diagnosis
Joseph R. Seibert, PhD and Raj P. Kapur, M.D. Ph.D., Children’s Hospital and Regional Medical Center, Seattle, WA

Session E    3:45 PM - 5:45 PM    Yosemite B
Fine Needle Aspiration in Pediatrics
John Buchino, MD, Kosair Children’s Hospital, Louisville, KY, and Ricardo Drut, M.D., Hospital de Ninos, Buenos Aires, Argentina

Session F    3:45 PM - 5:45 PM    Yosemite C
Selected Topics in Pediatric Hematopathology
Lila Penchansky, M.D., Presbyterian University Hospital, Pittsburgh, PA

Entry into the Workshops will require an admission card which will be collected by Convention Staff at the door. The Education Committee requests that Society members respect this policy and not attempt to enter without an admission card.

Positions Available

Minneapolis Children’s Medical Center
and The Children’s Hospital of St. Paul

Pediatric Pathologist

The successful candidate will be board certified in AP or AP/CP with subspecialty qualification in pediatric pathology, and have at least 10 years experience as an outstanding diagnostic pathologist at a major pediatric institution. Evidence of scholarly achievements in pediatric surgical pathology, hematopathology or perinatal pathology is highly desirable.

Pediatric Pathologist

The successful candidate will provide coverage for pediatric surgical pathology, perinatal and sutopay, hematopathology, as well as on-call support for the clinical laboratory. Subspecialty interest in hematopathology or perinatal pathology is desirable.

Clinical Pathologist

The successful candidate will be board certified in CP or AP/CP with at least 5 years of experience in directing clinical laboratory services. Interest and expertise in pediatric hematology is highly desirable. In addition to administrative responsibilities, the successful candidate will serve as a comprehensive resource for clinical laboratory consultations involving pediatric inpatients and outpatients. The clinical laboratories at Children’s perform approximately 400,000 tests annually.

The Children’s Hospitals and Clinics is a 270 bed pediatric health care provider created by the merger of the former Minneapolis Children’s Medical Center and the Children’s Hospital of St. Paul. The Division of Pathology is actively expanding to meet the needs of both inpatient and outpatient pediatric subspecialities including neonatology, cardiology, hematology/oncology, pulmonology, critical care, and gastroenterology. The Division of Pathology receives annually 7,000 surgical pathology and placental cases, performs 130-150 fetal and pediatric autopsies, and interprets over 700 bone marrow and blood smear specimens.

Please indicate position preference and submit a curriculum vitae, statement of area of expertise and interest, and names of three references to: Susan C. Simonton, M.D., Laboraotry Medical Director, Children’s-St. Paul, 345 North Smith Avenue, St. Paul, MN 55102. Equal Opportunity Employer.


The Aspen Conference on Pediatric Disease Presents Its Twenty-First Annual Meeting: Problems, Controversies and Recent Advances in Pediatric Pathology

The Institute for Pediatric Medical Education and the Society for Pediatric Pathology (SPP) will jointly sponsor a course on various aspects of the pathology of childhood diseases as part of the 21st Annual Aspen Conferences on Pediatric Disease. The week-long seminar will be held at the Gant in Aspen, CO from August 2-6, 1999 under the direction of Drs. Louis P. Dehner and Frederic B. Askin.

This course is designed primarily for general and pediatric pathologists but will be of interest to pediatric surgeons, radiologists, pediatricians and oncologists. Presentations will include discussions of the role of the fetal autopsy service, cystic renal diseases, congenital nephrotic syndrome, osteochondrodysplasias, cardiomyopathies, lysosomal storage diseases, EBV lymphadenopathies, congenital and acquired pulmonary diseases, liver developmental disorders, viral hepatitis and other hepatitides in children, surgical pathology of bony lesions, and adrenal gland pathology, among others. A microscopic slide set of 24 cases will be sent to participants prior to the conference, and the cases will be discussed in detail during a series of slide seminars. Participants may also submit cases for a “Case Presentation” session. A 250-300 page syllabus will be given to each participant as well. Faculty members include, J. Rutledge, E. Gilbert-Barness, M. Collins, L.P. Dehner, F.B. Askin, J.T. Stocker, A. Husain and R. Shikes.

This course, through the SPP, is accredited by the Accreditation Council for Continuing Medical Education (ACCME). The SPP certifies that this CME activity meets the criteria for 29 credit hours in category 1 for the Physician’s Recognition Award of the American Medical Association.

A special reduced tuition rate is available for members of the SPP until April 15. For further information, contact the Institute for Pediatric Medical Education, 6604 Landon Lane, Bethesda, MD 20817. Tel & Fax: 301-229-8338.

As part of the Aspen Conferences this summer, the SPP will also cosponsor a clinically oriented conference on “Pediatric Gastroenterology and Nutrition” to be held from July 26-30 at the Gant in Aspen. Information for this conference can also be obtained at the above address.

Future Pediatric Pathology Meetings

1999 Interim Meeting
Providence, RI
September 24-25, 1999

2000 Annual Meeting
New Orleans, LA
March 25-26, 2000

2000 Interim Meeting
Vancouver, British Columbia
Date to be determined - Fall 2000

2001 Annual Meeting
Atlanta, Georgia
March 2-3, 2001