Perspectives in Pediatric Pathology

Pathology of the Nervous System and Muscles in Fetuses, Infants, and Children

Volume 26 — 2007



Volume Editors: Hannah C. Kinney, James E. Dimmick, Beverly B. Rogers, Don B. Singer, Editors

Contents
Editorial Board i
Foreward
Don B. Singer, James E. Dimmick, Beverly B. Rogers
ii
ARTICLES
Tribute to Laurence Edward Becker, MD, FRCPC
Ernest Cutz
1
Founders of Pediatric Pathology - Marie Valdes-Dapena
M.Daria Haust, Enid F. Gilbert-Barness
4
Contributions of Larry E. Becker to Neuropathologic Research in the Sudden Infant Death Syndrome: A Tribute
Hannah C. Kinney
14
Abnormalities of the Brainstem Serotonergic System in the Sudden Infant Death Syndrome: A Review
Hannah C. Kinney
25
Central Nervous System Embryogenesis and Its Failures
Felicitas L. Lacbawan and Maximilian Muenke
42
Brain Malformations Associated with Cell Migration
Ilya M. Nasrallah, Jeffrey A. Golden*
64
Subclassification of Anencephalic Human Fetuses According to Morphology of the Posterior Cranial Fossa
Jens Fog Lomholt, Birgit Fischer-Hansen, Jean W. Keeling, Ingermarie Reintoft, Inger Kjaer
74
Agenesis of the Mesencephalon and Metencephalon with Cerebellar Hypoplasia: Putative Mutation in the EN2 Gene-Report of 2 Cases in Early Infancy
Harvey B. Sarnat, Denis R. Benjamin, Joseph R. Siebert, Gad B. Kletter, Sarah R. Cheyette
81
Alpha-synuclein expression in the developing human brain.
Ravi Raghavan, Loes de Kruijff, Monique D. Sterrenburg, Beverly B. Rogers, Christa L. Hladik and Charles L. White III
95
Epilepsy-Induced Microarchitectural Changes in the Brain
Dawna Duncan Armstrong
106
Temporal Soft Tissue Glioneuronal Heterotopia in a Child with a Seizure Disorder: Case Report and Review of the Literature
John A Ozolek, Joseph E Losee, Thelma C. Lopes, Csaba Galambos
114
Periventricular Leukomalacia: Overview and Recent Findings
Rebecca D. Folkerth
120
Evidence of Oxidative Stress in the Brains of Fetuses with CNS Anomalies and Islet Cell Hyperplasia
Patricia K. Hockett, Shawn Clark Emery, Lawrence Hansen, Eliezer Masliah
131
Apoptosis and White Matter Injury in Preterm Infants
Sangkae Chamnanvanaku, Linda R. Margraf, Dennis Burns, Jeffrey M. Perlman
140
Burden of Proof in the Postmortem Diagnosis of Mitochondrial Disease: Leigh Disease
Hannes Vogel
146
The Congenital Muscular Dystrophies: Recent Advances and Molecular Insights
Jerry R. Mendell, Daniel R. Boue, and Paul T. Martin
150
Mitochondrial Muscle Pathology
Kathleen Patterson
171
Prognostic Limitations of the Daumas-Duport Grading Scheme in Infratentorial Neuroglial Tumors in Children
Floyd H. Gilles , C. Jane Tavaré, Alan Leviton, E. Tessa Hedley-Whyte, Anna Sotrel, Lester Adelman, Richard L. Davis, Lucy B. Rorke and for The Childhood Brain Tumor Consortium
176
Tumors Associated with Sudden Infant and Childhood Death
Henry F. Krous, Amy E. Chadwick, and Hart Isaacs Jr.
187
Desmoplastic Noninfantile Ganglioglioma: Report of a Case
Ibrahim Qaddoumi, Eugene P. Ceppa, Asem Mansour, Maher A. Sughayer, Tarik Tihan
194
Glioneuronal Phenotype in a Diencephalic Pilomyxoid Astrocytoma
Jean-Pierre de Chadarévian*, Gregory E. Halligan, Goutham Reddy, Louise Bertrand, Judy M. Pascasio, Eric N. Faerber, Christos D. Katsetos
200
Molecular Basis of the Brain Tumor-Polyposis (Turcot) Syndrome
Stephen J. Qualman, Jay Bowen and Steven H. Erdman
207
C-kit Expression and Mutational Analysis in Medulloblastoma
Susan Chilton-MacNeill, Michael Ho, Cynthia Hawkins, Adam Gassas, Maria Zielenska ,Sylvain Baruchel
210
Extranodal Rosai-Dorfman Disease with Multifocal Bone and Epidural Involvement Causing Recurrent Spinal Cord Compression
Khulood Al-Saad, Paul Thorner, Bo-Yee Ngan, J. Ted Gerstle, Abhaya V. Kulkarni, Paul Babyn, Ronald M. Grant, Stanley Read, Ronald M. Laxer, Helen S. L. Chan
217
Heat-Accelerated Fixation and Rapid Dissection of the Pediatric Brain at Autopsy: A Pragmatic Approach to the Difficulties of Organ Retention
Ciara Barrett, Francesca Brett, David Grehan and Michael B. McDermott
223
Reference Values for Transverse Cerebellar Diameter Throughout Gestation
Halit Pinar, Sarah H. Burke, Carol W. Huang, Don B. Singer, and C. James Sung
228
Rulers Rule: Present and Future Applications of Cerebellar Morphometry
Joseph R. Siebert, Raj P. Kapur
233
Understanding Craniofacial Anomalies: The Etiopathogenesis of Craniosynostoses and Facial Clefting
Book Review by Geoffrey A. Machin
236
Robert P. Bolande In memoriam 239
INDEX 240









Chief/Director
Pathologist
Fellowship