Whether you are a Society for Pediatric Pathology (SPP) member or a visitor, we are glad you came to explore our site. This home page will let you know what is currently going on at the SPP, what has been added to the site, what new Meetings and Events have been listed, and what new Position ads have been recently posted. The Paediatric Pathology Society (PPS) comprises our European colleagues.

What's New
2014 SPP Spring Meeting Evaluations, SAM Post-tests, and CME/SAM Claim forms are still available. Please click here to log in. (Updated 3/2/14)
Latest SPP President's Message is now online. Please click here to read more.
Time to renew your SPP membership! If you haven't done so already, please click here to access.
Perspectives, Volume 28, Insights Into Pediatric Laboratory Medicine, and Volume 29, Soft Tissue Tumors in Children and Adolescents, can now be ordered online direct from Allen Press! Please click here to go to the Allen Press ordering page.

2015 Society for Pediatric Pathology Spring Meeting
March 21-22, 2015
Boston Marriott Copley Place
Boston, MA

Don't miss this opportunity to share your practice
experience and new discoveries with colleagues!

Housing and Transportation Information


Thank you for submitting your abstracts!

SPP Perinatal Pathology Course
Friday, April 17 - Sunday, April 19, 2015
Chicago, IL

Embassy Suites Downtown/Lakefront
511 N. Columbus Drive
Chicago, IL

Ona M. Faye-Petersen, M.D., Course Director
Linda Ernst, M.D., M.H.S., Assistant Course Director

Preliminary Agenda

Course Objectives

Hotel Information

Online Registration (Requires SPP Login)

Registration will include banquet, syllabi, and interaction with leading experts in the fields of perinatal medicine and perinatal pathology

Prospective new members: Interested in joining the SPP? The New Member online registration feature is currently being upgraded and is temporarily unavailable. Please click here for a PDF Membership Application.

For more information about membership options, please click here

Please note that membership dues are non-refundable

Please click the banner above to donate to the SPP now!

To learn more about our current fundraiser, please click here

Journal Watch
An eclectic selection of two dozen potentially interesting articles from current journals*

*Click here for the current watch list of journals.

All articles are in print. Please click the PMID number at the end of each citation to see the abstract on PubMed.

DISCLAIMER: Articles are listed in this section for information purposes only. The SPP does not approve or endorse these articles, and the SPP is not responsible for their content.

October 2014 Update
This month's Journal Watch prepared by Shelley Caltharp, M.D., Ph.D., Children's Healthcare of Atlanta, Atlanta, GA

Click here to download October 2014 Journal Watch list.

  • Horna P, Zhang L, Sotomayor EM, et al. Diagnostic immunophenotype of acute promyelocytic leukemia before and during early therapy with all-trans retinoic acid. Am J Clin Pathol. 2014 Oct;142(4):546-52. PMID: 25239423.
  • McElroy SJ, Castle SL, Bernard JK, et al. The ErbB4 ligand neuregulin-4 protects against experimental necrotizing enterocolitis. Am J Pathol. 2014 Oct;184(10):2768-78. PMID: 25216938.
  • Martin BA, Kerner JA, Hazard FK, et al. Evaluation of intestinal biopsies for pediatric enteropathy: A proposed immunohistochemical panel approach. Am Journal of Surg Path 2014 Oct;38(10):1387-95. PMID: 25188866.
  • Puls F, Niblett A, Marland G, et al. BCOR-CCNB3 (Ewing-like) sarcoma: A clinicopathologic analysis of 10 cases, in comparison with conventional Ewing sarcoma. Am J Surg Pathol. 2014 Oct;38(10):1307-18. PMID: 24805859.
  • Khoder A, Sarvaria A, Alsuliman A, et al. Regulatory B cells are enriched within the IgM memory and transitional subsets in healthy donors but are deficient in chronic GVHD. Blood. 2014 Sep 25;124(13):2034-45. PMID: 25051962.
  • Musselman JRB, Spector LG, Krailo MD, et al. The Children's Oncology Group Childhood Cancer Research Network (CCRN): Case catchment in the United States. Cancer. 2014 Oct;120(19):3007–15. PMID: 24889136.
  • Yamamoto S, Jaiswal M, Charng WL, et al. A Drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases. Cell. 2014 Sept; 159(1):200–14. PMID: 25259927.
  • Miyoshi K, Kohashi K, Fushimi F, et al. Close correlation between CXCR4 and VEGF expression and frequent CXCR7 expression in rhabdomyosarcoma. Hum Pathol. 2014 Sept;45(9): 1900-9. PMID: 25086956.
  • Bestas B, Moreno PM, Blomberg KE, et al. Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model. J Clin Invest. 2014 Sept;124(9):4067–81. PMID: 25105368.
  • Payne F, Colnaghi R, Rocha N, et al. Hypomorphism in human NSMCE2 linked to primordial dwarfism and insulin resistance. J Clin Invest. 2014 Sept;124(9):4028-38. PMID: 25105364.
  • Richardson RJ, Hammond NL, Coulombe PA, et al. Periderm prevents pathological epithelial adhesions during embryogenesis. J Clin Invest. 2014 Sept;124(9):3891–900. PMID: 25133425.
  • Vo KT, Matthay KK, Neuhaus J, et al. Clinical, biologic, and prognostic differences on the basis of primary tumor site in neuroblastoma: A report from the international neuroblastoma risk group project. J Clin Oncol. 2014 Oct;32(28):3169-76. PMID: 25154816.
  • Ismayilov V, Aksoy DY, Sayinalp N, et al. Increased soluble selectins as a reflection of activated platelets and endothelium in Legg-Calve-Perthes Disease. J Pediatr Hematol Oncol. 2014 Oct;36(7):410-1. PMID: 25000467.
  • Kolandijan NA, Wei C, Burke A, et al. Malignant melanoma in teenagers and young adults. J Pediatr Hematol Oncol. 2014 Oct;36(7):552-8. PMID: 25089601.
  • Wallenstein MB, Arain YH, Birnie KL, et al. Red blood cell transfusion is not associated with necrotizing enterocolitis: A review of consecutive transfusions in a tertiary neonatal intensive care unit . J Pediatr. 2014 Oct;165(4):678-82. PMID: 25039042.
  • Chiu YC, Liao SF, Wu JF, et al. Factors affecting the natural decay of hepatitis B surface antigen in children with chronic hepatitis B virus infection during long-term follow-up J Pediatr. 2014 Oct;165(4):767-72. PMID: 25112693.
  • He X, Zhang L, Chen Y, et al. The G protein α subunit G α s is a tumor suppressor in Sonic hedgehog−driven medulloblastoma. Nature Medicine 20, 1035–1042 (2014) PMID: 25150496.
  • Wein N, Vulin A, Falzarano MS, et al. Translation from a DMD exon 5 IRES results in a functional dystrophin isoform that attenuates dystrophinopathy in humans and mice. Nat Med. 2014 Sep;20(9):992-1000. PMID: 25108525.
  • Madhi SA, Cutland CL, Kuwanda L, et al. Influenza vaccination of pregnant women and protection of their infants. N Engl J Med. 2014 Sep 4;371(10):918-31. PMID: 25184864.
  • Mengelbier LH, Bexell D, Sehic D, et al. Orthotopic Wilms tumor xenografts derived from cell lines reflect limited aspects of tumor morphology and clinical characteristics. Pediatr Blood Cancer. 2014 Nov;61(11):1949–54. PMID: 25044705.
  • Uijterschout L, Swinkels DW, Domell๖f M, et al. Serum hepcidin measured by immunochemical and mass-spectrometric methods and their correlation with iron status indicators in healthy children aged 0.5–3 y. Pediatr Res. 2014 Oct;76(4):409-14. PMID: 25116229.
  • Ma X, Barboza LA, Siyahian A, et al. Tetralogy of Fallot: aorto-pulmonary collaterals and pulmonary arteries have distinctly different transcriptomes. Pediatr Res. 2014 Oct;76(4):341–6. PMID: 25000348.
  • Saeed S, Quintin J, Kerstens HH, et al. Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity. Science. 2014 Sep 26;345(6204):1251086. PMID: 25258085.

September 2014 Update
This month's Journal Watch prepared by Jefferson Terry, MD, PhD, FRCPC, McMaster University Medical Center, Hamilton, Ontario.

Click here to download September 2014 Journal Watch list.

  • Williams AS, Hache KD. Recognition and discrimination of tissue-marking dye color by surgical pathologists: recommendations to avoid errors in margin assessment. Am J Clin Pathol. 2014 Sep;142(3):355-61. PMID: 25125626.
  • Yasir S, Gamez R, Jenkins S, et al. Significant histologic features differentiating cellular fibroadenoma from phyllodes tumor on core needle biopsy specimens. Am J Clin Pathol. 2014 Sep;142(3):362-9. PMID: 25125627.
  • Hollman-Hewgley D, Lazare M, Bordwell A, et al. A single slide multiplex assay for the evaluation of classical hodgkin lymphoma. Am J Surg Pathol. 2014 Sep;38(9):1193-202. PMID: 24854113.
  • Arnold MA, Schoenfield L, Limketkai BN, Arnold CA. Diagnostic Pitfalls of Differentiating Desmoplastic Small Round Cell Tumor (DSRCT) From Wilms Tumor (WT): Overlapping Morphologic and Immunohistochemical Features. Am J Surg Pathol. 2014 Sep;38(9):1220-6. PMID: 24832162.
  • Miyoshi K, Kohashi K, Fushimi F, et al. Close correlation between CXCR4 and VEGF expression and frequent CXCR7 expression in rhabdomyosarcoma. Hum Pathol. 2014 Sep;45(9):1900-9. PMID: 25086956.
  • Schaeffer DF, Walsh JC, Kirsch R, et al. Distinctive histopathologic phenotype in resection specimens from patients with Crohn's disease receiving anti-TNF- α therapy. Hum Pathol. 2014 Sep;45(9):1928-35. PMID: 25022570.
  • Cheson BD, Fisher RI, Barrington SF, et al. Recommendations for Initial Evaluation, Staging, and Response Assessment of Hodgkin and Non-Hodgkin Lymphoma: The Lugano Classification. J Clin Oncol. 2014 Aug 11. PMID: 25113753.
  • Schleiermacher G 1, Javanmardi N 2, Bernard V, et al. Emergence of New ALK Mutations at Relapse of Neuroblastoma. J Clin Oncol. 2014 Sep 1;32(25):2727-34. PMID: 25071110.
  • Zwerdling T, Won E, Shane L, Javahara R, Jaffe R . Langerhans cell sarcoma: case report and review of world literature. J Pediatr Hematol Oncol. 2014 Aug;36(6):419-25. PMID: 24942035.
  • Boussemart L, Malka-Mahieu H, Girault I, et al. eIF4F is a nexus of resistance to anti-BRAF and anti-MEK cancer therapies. Nature. 2014 Sep 4;513(7516):105-9. PMID: 25079330.
  • Wein N, Vulin A, Falzarano MS, et al. Translation from a DMD exon 5 IRES results in a functional dystrophin isoform that attenuates dystrophinopathy in humans and mice. Nat Med. 2014 Sep;20(9):992-1000. PMID: 25108525.
  • He X, Zhang L, Chen Y, et al. The G protein α subunit G α s is a tumor suppressor in Sonic hedgehog-driven medulloblastoma. Nat Med. 2014 Sep;20(9):1035-42. PMID: 25150496.
  • Meany HJ, London WB, Ambros PF, et al. Significance of clinical and biologic features in Stage 3 neuroblastoma: A report from the International Neuroblastoma Risk Group project. Pediatr Blood Cancer. 2014 Sep;(61)11:1932-9. PMID: 25044743.
  • Leite FA, Lira RC, Fedatto PF, et al. Low expression of HLA-DRA, HLA-DPA1, and HLA-DPB1 is associated with poor prognosis in pediatric adrenocortical tumors (ACT). Pediatr Blood Cancer. Pediatr Blood Cancer. 2014 Sep;(61)11:1940-8. PMID: 25156210.
  • Cimino PJ, Agarwal A, Dehner LP . Myxopapillary ependymoma in children: A study of 11 cases and a comparison with the adult experience. Pediatr Blood Cancer. 2014 Sep;(61)11:1969-71. PMID: 25066546.
  • Underwood MA, Arriola J, Gerber CW, et al. Bifidobacterium longum subsp. infantis in experimental necrotizing enterocolitis: alterations in inflammation, innate immune response, and the microbiota. Pediatr Res. 2014 Oct;76(4):326-33. PMID: 25000347.

Click here for previous journal watch listings.

From the Editor's Desk

Dear Colleagues:

Late fall greetings! The SPP 2015 Spring Meeting will be held at the Boston Marriott Copley Place, Boston, MA, on March 21 and 22, 2015. Abstract submission is now open. You can submit your abstract by clicking here. Abstract submission will close on Thursday, November 20, 2014, at 11:59 P.M. Central Time. Housing and transportation information is available by clicking here.

By all accounts the Fall Joint Meeting of PPS and SPP, held September 4 through 6, 2014, at Birmingham UK was very successful. Congratulations to all of the SPP Award winners announced at the meeting. Award winners are listed in the most recent report from Fusun Gundogan of the Distinctions and Awards Committee, which can be viewed by clicking here. If I may, I would like to offer a special tip of the hat to Bahig Shehata for winning the Harry B. Neustein Memorial Award for an unprecedented third time (2008, 2010, and 2014).

Robert E Ruiz
SPP Website Editor

Questions and comments about website content can be directed to the website editor. Technical concerns can be directed to the site webmaster.