Harry B. Neustein Memorial Award

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The purpose of this award was originally to recognize abstracts presenting meritorious work involving electron microscopy in the study of disorders of children. In 1998 the award criteria were expanded to in addition include new methodological advances in molecular technology and immunohistochemical techniques or development of other innovative technological advances in the study of pediatric pathology. Platform or poster presentation at the interim or annual SPP meeting qualify provided the winner is the principal author and the work has been identified as being in competition for the award by the abstract committee. The winner receives an illuminated certificate, $500.00 cash award and receives recognition in the Society Newsletter.

Neustein Award Recipients

Year Name Title
1990 Daphne E. deMello, MD, Cardinal Glennon Children’s Hospital Subcellular immuno-gold localization of SP-A in lungs of infants dying from respiratory distress syndrome.
1991 None None
1992 Catherine Pegors, MD Morphology of the middle and inner ear in a murine model of mucopolysaccharidase type VII.
1993 Gary Mireau, PhD, Denver Children’s Hospital Intranuclear Birbeck granules in Langerhans cell histiocytosis.
1994 None None
1995 None None
1996, Spring Joe C. Rutledge, MD, Children’s Orthopedic Hospital and Medical Center Ultrastructural changes after bone marrow transplantation for Hurler’s disease.
1996, Fall None None
1997, Spring None I-Cell Disease - A Pathologic and Electron Microscopic Study of 5 Cases.
1997, Fall None None
1998, Spring None None
1998, Fall None None
1999, Spring Elizabeth Perlman, MD, Johns Hopkins, Baltimore Genetic analysis of clear cell sarcoma of kidney (CCSK) by comparative genomic hybridization (CGH).
1999, Fall None None
2000, Spring

P. Argani, Johns Hopkins Medical Inst., Baltimore, MD; John M. Hicks, Texas Children’s Hospital, Houston, TX

Reassessment of infantile fibrosarcoma and related lesions by RT-PCR for the ETV6/NTRK3 fusion transcript Role of ICAM-1deficiency in modulation of lupus-like glomerulopathy: A histopathologic and ultrastructural study.
2000, Fall Pam Groen & David Witte, Childrens Hospital Medical Center, Cincinnati Quantitative EBV assay using the LightCycler instrument to monitor transplant patients at risk for PTLD.
2001, Spring Sara O. Vargas, MD, Boston Children’s Hospital, Boston, MA Optical “biopsy” of the pediatric gastrointestinal tract using optical coherence tomography
2001, Fall Allen Yeoh, MD, St. Jude’s Children’s Research Hospital, Memphis, TN Molecular fingerprinting for subclassification in childhood acute lymphoblastic leukemia using the Affymetrix gene-chip.
2002, Spring Kenichi Harada & Anirban Maitra, UT Southwestern, Dallas, TX Promoter methylation of CASPASEI and RASSF1A is a common event in solid tumors of children.
2002, Fall Philip J Katzman, MD, University of Rochester Medical Center, Rochester, NY Cardiac registry screening for DiGeorge critical region deletion using loss of heterozygosity (LOH) analysis.
2003, Spring Chiler Hasan, MS, Children's Memorial Hospital, Northwestern University, Chicago, IL Differences in Genetic Expression Between Hyperplastic Perilobar Nephrogenic Rest (HPLNR) and Wilms Tumor (WT).

2003, Fall

None None
2004, Spring Rocio Pena-Alonso M.D., Hospital Infantil de Mexico Federico Gomez and Hospital General de Mexico, Mexico, D.F. Analysis of the sex determining region of chromosome-Y (SRY) by PCR and FISH in true hermaphrodites.
2004, Fall Dinesh Rakheja, M.D., UT Southwestern and Children’s Medical Center Dallas, TX Batten disease and lipid rafts
2005, Spring Rene L. Galindo, M.D., Children’s Medical Center of Dallas, Dallas, TX Genetic dissection of alveolar rhabdomyosarcoma pathogenesis in Drosophila melanogaster.
2005, Fall Nancy Galvin, Ph.D., St Louis University, St. Louis, MO Early onset of lysosomal storage disease in a murine model of mucopolysaccharidosis type VII: Undegraded substrate accumulates in many tissues in the fetus and very young Mps VII mouse.
2006, Spring Nina Tatevian, M.D., Ph.D., Baylor College of Medicine, Texas Children’s Hospital, Houston, TX Molecular heterogeneity in a poorly differentiated neuroblastoma with pleomorphic giant cells-a Bac array CGH analysis
2006, Fall Monique E. DePaepe, M.D., Brown Medical School, Women and Infants Hospital, Providence, RI Microarray analysis of ventilated preterm lungs identifies differential expression of angiogenesis-related genes.
2007, Spring Amanda Murphy, M.D., Hospital for Sick Children, Toronto, ON Variable expression of WT1 in desmoplastic small round cell tumour.
2007, Fall Gino R. Somers. M.D., University of Toronto, Toronto, ON Detailed expression profiling of pediatric undifferentiated sarcomas: Evidence for upregulation of the insulin-like growth factor signaling pathway.
2008, Spring Scott D. Boyd, M.D., Stanford University Stanford, CA Characterization of Pre-B cell acute lymphoblastic leukemia micro RNA libraries using high-throughput pyrosequencing and specimen barcoding.
2008, Fall Bahig Shehata, M.D., Children’s Healthcare of Atlanta, Atlanta, GA Ewing sarcoma with 7;22 translocation-Is it occurring in a younger age group with predilection for extraskeletal location? A study of 35 cases with emphasis
2009, Spring C. A. French, M.D., Brigham and Women’s Hospital & Dana-Farber Cancer Institute, Boston, MA Targeting the Epigenome in NUT Midline Carcinoma.
2010, Spring Bahig Shehata, MD, Children’s Healthcare/Egleston Atlanta, Georgia Identification of candidate genes for histiocytoid cardiomyopathy using whole genome analysis: Analyzing material from the HC Registry
 
Kyle C Kurek, Children’s Hospital Boston Harvard Medical School Boston, MA
Garry W. Mierau (runner-up), Children’s Hospital Aurora, CO

Loss of function mutations in PTPN11 is responsible for the hereditary bone tumor syndrome, metachondromatosis.

Comparative evaluation of specimen collection methods for ultrastructural diagnosis of primary ciliary dyskinesia syndrome.

2011, Spring Bonnie Cole, University of Washington Seattle, Washington 19q13.4 loss of heterozygosity and occult androgenic/biparental mosaicism in sporadic hepatic mesenchymal hamartoma
2011, Fall Larissa V. Furtado, MD University of Utah and ARUP Labs Salt Lake City, Utah Development of a DNA Microsatellite Genotyping Test for Aneuploidy Detection in Paraffin Embedded Tissue from Products of Conception
2012, Spring Craig Midgen, MD, Texas Children’s Hospital and Baylor College of Medicine Houston, Texas Ventricular noncompaction with and without associated cardiac abnormalities: A pathology series of 30 cases.
2012, Fall Benjamin Wilkins, M.D., Children’s Hospital Philadelphia Philadelphia, PA Zebrafish cirhin morphants have p53-mediated developmental biliary defects, and are a model for North American Indian Childhood Cirrhosis
2013, Spring Csaba Galambos, MD, PhD, Children’s Hospital Pittsburgh Pittsburgh, PA In utero embryonic intracardiac injection under biomicroscopy guidance: a cutting edge technology to study embryonic lung development in vivo.
2013, Fall Jason Wang, MD, Children’s Medical Center of Dallas, Dallas, TX Diagnostic yield of targeted panels of seizure genes
2014, Spring Ilana Ariel, MD, Hadassah-Hebrew University The “myotrophoblast” – endothelin-1-induced contraction of modified spiral artery of the rat.
2014, Fall Bahig M Shehata, MD, Emory University School of Medicine, Children’s Healthcare of Atlanta Knockdown of ndufb11 in zebrafish model results in cardiac anomalies, confirming the role of newly recognized NDUFB11 in histiocytoid cardiomyopathy pathogenesis
2015, Spring Gino Somers, MBBS, PhD, Hospital for Sick Children University of Toronto Toronto, Canada Sarcoma subgrouping by detection of fusion transcripts using nanostring technology
2015, Fall Seth C Lummus, D.O., M.S., Children’s Hospital Colorado Aurora, CO Elevated cell cycle and muted host immunity underlie the biology of infant ependymomas.
2016, Spring Miguel Reyes-Múgica, M.D., Children’s Hospital of Pittsburg, Pittsburgh, PA Serotonin induces proliferation in NRASmutated nevus cells from patients with large/giant congenital melanocytic nevi
2016, Fall Rangaraj Selvarangan, M.D., Children’s Mercy Hospital Kansas City, MO Human parechovirus 3 is the leading Picornavirus associated with CNS infections in children
2017, Spring Michael Fritsch, M.D., Ph.D., Northwestern University Chicago, IL Correlating MR imaging and histology in a rat model of placental dysfunction due to diminished maternal vascular perfusion
2017, Fall Nicholas Willard, M.D., University of Colorado Denver, CO Transcriptomic analysis for molecular subgrouping of former CNS-PNETs
2018, Spring Sarah Kerr, M.D., Mayo Clinic Rochester, MN Villitis of Unknown Etiology Demonstrates an Inflammatory Signature Similar to Graft Versus Host Disease and Allograft Rejection
2018, Fall Nathan Shelman, MD, Boston Children’s Hospital, Boston, MA H3K27me3 in the Pathologic Investigation of Disorders of Sexual Development
2019, Spring Linda Ernst, MD, NorthShore University HealthSystem, Evanston, IL Umbilical cord blood miRNAs to predict neonatal early onset sepsis
2019, Fall Csaba Galambos, MD, PhD, Children's Hospital Colorado, Aurora, CO State-of-the-Art Synchrotron-based Imaging Uncovers the Three-Dimensional Microanatomy of Pediatric PulmonaryVascular Disease
2020, Spring Claudia Salgado, MD, PhD, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA DNA methylation and copy number profiling in pediatric BCOR-ITD
2020, Fall Terry Morgan, MD, PhD, Oregon Health & Science University, Portland, OR Placental cell-specific extracellular vesicle profiles from syncytiotrophoblasts and extravillous trophoblasts in the first trimester
2021, Spring Siddhartha Sen, MD, PhD, Baylor College of Medicine Texas Children’s Hospital Houston, Texas High-Depth Tissue-Based Testing for Molecular Diagnosis of Disorders of Somatic Mosaicism
2021, Fall

Nicholas Willard, DO, Children’s Hospital Colorado, Aurora, CO

Spatial Gene Expression in Childhood Ependymoma Reveals Tumor Cell Subpopulations and Their Locations In Situ